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Fig. 4 | BMC Medicine

Fig. 4

From: A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP)

Fig. 4

Bayesian predictive probability of the unfavourable outcome being less than a specific threshold, p1, in a future phase III trial of 500 patients per arm, following various observed proportions of unfavourable outcomes and patient numbers in a STEP trial of equal treatment duration. Solid lines correspond to a sceptical prior and dashed lines to the flat prior

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