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Table 2 Psychophysical summary of temperature thresholds necessary to produce ratings at each condition in a sex-age matched sample of people with and without Alzheimer’s disease

From: Contact heat sensitivity and reports of unpleasantness in communicative people with mild to moderate cognitive impairment in Alzheimer’s disease: a cross-sectional study

  Total (N = 80) Control (N = 40) AD (N = 40) p-value Cohen’s d
  Median [IQR] Median [IQR] Median [IQR]   
Just-noticeable warmth      
 Temperature 33.0 [32–35] 32.0 [32–34] 34.0 [33–36] 0.002 0.64
 Affect 0.0 [0–2] 0.0 [0–2] 0.0 [0–1] 0.846 0.04
Weak pain      
 Temperature 37.0 [35–41] 35.5 [34–39] 39.0 [35–42] 0.016 0.51
 Affect 4.0 [0–5] 3.3 [0–5] 4.0 [1–6] 0.402 0.18
Moderate pain      
 Temperature 42.0 [38–45] 40.0 [38–44] 43.0 [39–45] 0.043 0.45
 Affect 6.0 [5–8] 6.0 [5–8] 6.5 [4–9] 0.867 0.04
  1. Temperature was measured in degrees Celsius (range = 30–55 °C). Affect is the affective distress measured via a 0–20 Unpleasantness scale (0 = neutral, 20 = extremely unpleasant). The p-value was derived from a Mann–Whitney U Test. AD Alzheimer’s disease, IQR interquartile range