Table 1 Sample characteristics by SF36-VT quartiles of 18,101 EPIC-Norfolk participants
Characteristic | N | Total | Q1 (76–100) | Q2 (65–75) | Q3 (50–64) | Q4 (0–49) | p-value |
|---|---|---|---|---|---|---|---|
Agea (years) | 18,101 | 59.0 ± 9.1 | 59.2 ± 8.7 | 59.0 ± 9.1 | 59.2 ± 9.3 | 58.6 ± 9.4 | 0.008 |
Sex | 18,101 | <0.001 | |||||
Male | 7943 (43.9) | 2186 (49.7) | 2322 (46.0) | 1842 (40.9) | 1593 (38.3) | ||
Female | 10,158 (56.1) | 2209 (50.3) | 2725 (54.0) | 2659 (59.1) | 2565 (61.7) | ||
Body mass index (kg/m2) | 18,064 | <0.001 | |||||
<18.5 | 83 (0.5) | 13 (0.3) | 19 (0.4) | 23 (0.5) | 28 (0.7) | ||
18.5–25 | 7234 (40.1) | 1891 (43.1) | 2078 (41.2) | 1721 (38.3) | 1544 (37.3) | ||
25–30 | 8123 (45.0) | 2029 (46.3) | 2289 (45.4) | 2021 (44.9) | 1784 (43.1) | ||
>30 | 2624 (14.5) | 451 (10.3) | 654 (13.0) | 732 (16.3) | 787 (19.0) | ||
Education | 18,094 | <0.001 | |||||
Lower than A-level | 8255 (45.6) | 1912 (43.5) | 2232 (44.3) | 2065 (45.9) | 2046 (49.2) | ||
At least A-level | 9839 (54.4) | 2481 (56.5) | 2812 (55.8) | 2435 (54.1) | 2111 (50.8) | ||
Married | 18,009 | <0.001 | |||||
Yes | 14,681 (81.5) | 3613 (82.6) | 4184 (83.4) | 3648 (81.5) | 3236 (78.2) | ||
Nob | 3328 (18.5) | 763 (17.4) | 834 (16.6) | 830 (18.5) | 901 (21.8) | ||
Social Class | 17,757 | <0.001 | |||||
Manual | 6725 (37.9) | 1561 (36.2) | 1778 (35.9) | 1696 (38.4) | 1690 (41.5) | ||
Non-manual | 11,032 (62.1) | 2753 (63.8) | 3178 (64.1) | 2716 (61.6) | 2385 (58.5) | ||
Physical activity | 18,101 | <0.001 | |||||
Inactive | 5226 (18.7) | 1019 (23.2) | 1321 (26.2) | 1372 (30.5) | 1514 (36.4) | ||
Moderately inactive | 5287 (23.3) | 1246 (28.4) | 1519 (30.1) | 1324 (29.4) | 1198 (28.8) | ||
Moderately active | 4210 (29.2) | 1092 (24.8) | 1230 (24.4) | 1022 (22.7) | 886 (20.8) | ||
Active | 3378 (28.9) | 1038 (23.6) | 977 (19.4) | 783 (17.4) | 580 (13.9) | ||
Depression | 18,101 | <0.001 | |||||
Yes | 2554 (14.1) | 315 (7.2) | 547 (10.8) | 645 (14.3) | 1047 (25.2) | ||
No | 15,547 (85.9) | 4080 (92.8) | 4500 (89.2) | 3856 (85.7) | 3111 (74.8) | ||
Diabetes | 18,101 | <0.001 | |||||
Yes | 392 (2.2) | 77 (1.8) | 92 (1.8) | 101 (2.2) | 122 (2.9) | ||
No | 17,709 (97.8) | 4318 (98.3) | 4955 (98.2) | 4400 (97.8) | 4036 (97.1) | ||
Bodily pain (SF36) | 18,080 | 74.5 ± 23.0 | 87.7 ± 15.5 | 79.7 ± 18.8 | 70.7 ± 21.8 | 57.7 ± 24.6 | <0.001 |
Fruit and vegetable consumption (g/day) | 17,621 | 522.6 ± 257.0 | 539.8 ± 270.6 | 527.8 ± 245.2 | 517.8 ± 252.9 | 503.0 ± 259.3 | <0.001 |
Alcohol consumption (g/day) | 17,621 | 8.6 ± 12.7 | 9.3 ± 13.4 | 9.1 ± 12.8 | 8.2 ± 12.3 | 7.7 ± 12.4 | <0.001 |
Beta blocker use | 18101 | <0.001 | |||||
Yes | 1138 (6.3) | 215 (4.9) | 278 (5.5) | 323 (7.2) | 322 (7.7) | ||
No | 16,963 (93.7) | 4180 (95.1) | 4769 (94.5) | 4178 (92.8) | 3836 (92.3) | ||
Thyroid stimulating hormone (mU/L) | 9761 | 0.265 | |||||
High (≥4) | 8857 (90.7) | 2191 (90.35) | 2445 (90.2) | 2246 (91.7) | 1975 (90.8) | ||
Low (<4) | 904 (9.3) | 234 (90.7) | 266 (9.8) | 204 (8.3) | 200 (9.2) | ||
CRP (mg/L) | 12,993 | 3.1 ± 6.2 | 3.1 ± 5.6 | 3.1 ± 6.4 | 2.9 ± 5.4 | 3.3 ± 7.3 | 0.223 |
Haemoglobin (g/dL) | 12,971 | 0.886 | |||||
High (≥11) | 12,793 (98.6) | 3138 (98.7) | 3553 (98.5) | 3220 (98.7) | 2882 (98.6) | ||
Low (<11) | 178 (1.37) | 41 (1.3) | 54 (1.5) | 43 (1.3) | 40 (1.4) |