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Table 1 Sample characteristics by SF36-VT quartiles of 18,101 EPIC-Norfolk participants

From: Fatigue is associated with excess mortality in the general population: results from the EPIC-Norfolk study

Characteristic N Total Q1 (76–100) Q2 (65–75) Q3 (50–64) Q4 (0–49) p-value
Agea (years) 18,101 59.0 ± 9.1 59.2 ± 8.7 59.0 ± 9.1 59.2 ± 9.3 58.6 ± 9.4 0.008
Sex 18,101       <0.001
 Male   7943 (43.9) 2186 (49.7) 2322 (46.0) 1842 (40.9) 1593 (38.3)
 Female   10,158 (56.1) 2209 (50.3) 2725 (54.0) 2659 (59.1) 2565 (61.7)
Body mass index (kg/m2) 18,064       <0.001
 <18.5   83 (0.5) 13 (0.3) 19 (0.4) 23 (0.5) 28 (0.7)
 18.5–25   7234 (40.1) 1891 (43.1) 2078 (41.2) 1721 (38.3) 1544 (37.3)
 25–30   8123 (45.0) 2029 (46.3) 2289 (45.4) 2021 (44.9) 1784 (43.1)
 >30   2624 (14.5) 451 (10.3) 654 (13.0) 732 (16.3) 787 (19.0)
Education 18,094       <0.001
 Lower than A-level   8255 (45.6) 1912 (43.5) 2232 (44.3) 2065 (45.9) 2046 (49.2)
 At least A-level   9839 (54.4) 2481 (56.5) 2812 (55.8) 2435 (54.1) 2111 (50.8)
Married 18,009       <0.001
 Yes   14,681 (81.5) 3613 (82.6) 4184 (83.4) 3648 (81.5) 3236 (78.2)
 Nob   3328 (18.5) 763 (17.4) 834 (16.6) 830 (18.5) 901 (21.8)
Social Class 17,757       <0.001
 Manual   6725 (37.9) 1561 (36.2) 1778 (35.9) 1696 (38.4) 1690 (41.5)
 Non-manual   11,032 (62.1) 2753 (63.8) 3178 (64.1) 2716 (61.6) 2385 (58.5)
Physical activity 18,101       <0.001
 Inactive   5226 (18.7) 1019 (23.2) 1321 (26.2) 1372 (30.5) 1514 (36.4)
 Moderately inactive   5287 (23.3) 1246 (28.4) 1519 (30.1) 1324 (29.4) 1198 (28.8)
 Moderately active   4210 (29.2) 1092 (24.8) 1230 (24.4) 1022 (22.7) 886 (20.8)
 Active   3378 (28.9) 1038 (23.6) 977 (19.4) 783 (17.4) 580 (13.9)
Depression 18,101       <0.001
 Yes   2554 (14.1) 315 (7.2) 547 (10.8) 645 (14.3) 1047 (25.2)
 No   15,547 (85.9) 4080 (92.8) 4500 (89.2) 3856 (85.7) 3111 (74.8)
Diabetes 18,101       <0.001
 Yes   392 (2.2) 77 (1.8) 92 (1.8) 101 (2.2) 122 (2.9)
 No   17,709 (97.8) 4318 (98.3) 4955 (98.2) 4400 (97.8) 4036 (97.1)
Bodily pain (SF36) 18,080 74.5 ± 23.0 87.7 ± 15.5 79.7 ± 18.8 70.7 ± 21.8 57.7 ± 24.6 <0.001
Fruit and vegetable consumption (g/day) 17,621 522.6 ± 257.0 539.8 ± 270.6 527.8 ± 245.2 517.8 ± 252.9 503.0 ± 259.3 <0.001
Alcohol consumption (g/day) 17,621 8.6 ± 12.7 9.3 ± 13.4 9.1 ± 12.8 8.2 ± 12.3 7.7 ± 12.4 <0.001
Beta blocker use 18101       <0.001
 Yes   1138 (6.3) 215 (4.9) 278 (5.5) 323 (7.2) 322 (7.7)
 No   16,963 (93.7) 4180 (95.1) 4769 (94.5) 4178 (92.8) 3836 (92.3)
Thyroid stimulating hormone (mU/L) 9761       0.265
 High (≥4)   8857 (90.7) 2191 (90.35) 2445 (90.2) 2246 (91.7) 1975 (90.8)
 Low (<4)   904 (9.3) 234 (90.7) 266 (9.8) 204 (8.3) 200 (9.2)
CRP (mg/L) 12,993 3.1 ± 6.2 3.1 ± 5.6 3.1 ± 6.4 2.9 ± 5.4 3.3 ± 7.3 0.223
Haemoglobin (g/dL) 12,971       0.886
 High (≥11)   12,793 (98.6) 3138 (98.7) 3553 (98.5) 3220 (98.7) 2882 (98.6)
 Low (<11)   178 (1.37) 41 (1.3) 54 (1.5) 43 (1.3) 40 (1.4)
  1. p values indicate levels of significance across all quartiles
  2. Data presented as mean (SD) for all continuous variables and number (%) for categorical variables
  3. aat SF36 completion bincludes single, widowed, seperated and divorced