Serum levels of mitochondrial inhibitory factor 1 are independently associated with long-term prognosis in coronary artery disease: the GENES Study

Table 1 Clinical and biological characteristics in coronary artery disease patients when they were first included in the GENES study

	Alive (n = 407)	Dead (n = 170)	P
Age, years	59.5 (7.8)	62.9 (8.0)	0.03
School, years of education	9.7 (3.0)	9.2 (2.6)	0.03^b
Smoking, pack year	31.3 (31.1)	49.3 (44.1)	0.001^b
Alcohol, g/day	28.4 (31.6)	28.7 (29.6)	0.93
Physical activity (high level), %	14.3	5.3	0.003
Treatment for diabetes, %	19.4	36.5	0.001
Treatment for dyslipidemia, %	67.6	56.5	0.02
Treatment for hypertension, %	42.7	50.0	0.12
BMI, kg/m²	27.3 (3.8)	27.7 (4.4)	0.27
Waist circumference, cm	97.9 (10.0)	101.5 (12.7)	0.001
Systolic blood pressure, mm Hg	139.2 (20.1)	139.8 (22.0)	0.77
Heart rate, beats/min	62.2 (10.6)	67.1 (13.3)	0.001^a
Fasting glucose, mmoL/L	5.69 (1.58)	6.41 (2.72)	0.06^b
Triglycerides, g/L	1.66 (0.88)	1.57 (0.80)	0.17^a
Total cholesterol, g/L	2.01 (0.41)	1.94 (0.43)	0.06
LDL-C, g/L	1.25 (0.35)	1.20 (0.39)	0.13
HDL-C, g/L	0.43 (0.12)	0.43 (0.11)	0.42
Lipoprotein(a) ≥ 0.30 vs. < 0.30 g/L, %	55.8	47.7	0.08
eGFR < 30 mL/min, %	0.5	4.7	0.002^c
hs-CRP ≥ 5 mg/L vs. < 5 mg/L, %	51.6	64.1	0.006
hs-TnT, pg/mL	145.9 (386.2)	198.1 (469.1)	0.002^b
NT-proBNP, pg/mL	383.3 (683.1)	1253.9 (2347.5)	0.001^b
ABI ≤ 0.9, %	29.7	47.1	0.001
LVEF ≥ 50 %, %	77.2	49.4	0.001
Gensini score	43.8 (37.3)	57.3 (46.3)	0.003^a
Duration of coronary artery disease, months	33.4 (57.2)	57.6 (73.2)	0.001^b
IF1, mg/L	0.44 (0.12)	0.41 (0.13)	0.03

Data are expressed in mean (SD) or %
BMI body mass index, eGFR estimated Glomerular Filtration Rate, hs-CRP high-sensitivity C-Reactive Protein, hs-TnT high-sensitivity cardiac troponin T, NT-proBNP N-terminal pro-brain natriuretic peptide, ABI Ankle-brachial index, LVEF Left Ventricular Ejection Fraction
^alog transformed data, ^bWilcoxon–Mann–Whitney test, ^cFischer’s exact test

ISSN: 1741-7015