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Table 1 Cohort characteristics according to adherence to the Mediterranean diet at baseline of the EPIC-Norfolk Study (n = 23,902)

From: Prospective association of the Mediterranean diet with cardiovascular disease incidence and mortality and its population impact in a non-Mediterranean population: the EPIC-Norfolk study

Characteristics

Mediterranean diet score (MDS), basis of scoringa

The Mediterranean diet pyramid (PyrMDS)

Published literature (LitMDS)

Medians of dietary intake (mMDS)

Tertiles of dietary intake (tMDS)

Low

High

Low

High

Low

High

Low

High

n = 7898

n = 7898

n = 7730

n = 8351

n = 7903

n = 6266

n = 8927

n = 8574

Age (years)

59.4 (9.4)

58.2 (9.0)c

58.8 (9.4)

58.6 (9.1)

59.2 (9.3)

58.4 (9.1)c

59.1 (9.3)

58.7 (9.1)c

Sex, men (%)

56

32c

58

32c

44

45

46

42c

Education level (%)

 School until age 16 years

10

11

10

10

11

11

10

10

 School until age 18 years

38

42

40

42

38

43

38

43

 Bachelor’s degree or above

8

19c

10

16c

10

17c

10

17c

Marital status, married (%)

84

79c

83

80c

80

83

81

82

Smoking status (%)

 Current

16

8

17

8

16

7

15

8

 Former

42

41c

42

41c

38

45c

38

45c

Physical activity level (%)

 Moderately inactive

26

31

27

30

28

29

28

30

 Moderately active

23

24

23

24

22

24

22

24

 Active

19

19c

19

19c

17

22c

17

20c

Occupational status (%)

 Unskilled worker

6

3

5

4

6

3

6

3

 Skilled worker

63

52

60

54

61

53

61

51

 Manager or equivalent

28

39

30

38

29

38

28

39

 Professional

4

5c

4

5c

4

5c

4

5c

Family history of diabetes (%)

13

13

13

13

13

14

13

13

Family history of MI (%)

34

39c

34

38c

34

39c

35

38c

Family history of stroke (%)

24

25

24

25

24

24

24

24

Season of FFQ administered (%)

 Spring

27

27

26

28

26

27

27

27

 Summer

24

26

24

26

25

26

25

25

 Autumn

25

25b

26

25

25

25

25

25

Prevalent diabetes (%)

3

3

2

4c

3

3b

2

3c

Use of anti-hypertensive drug (%)

16

16

15

17c

16

17

16

17b

Use of lipid-lowering drug (%)

1

1c

1

2c

1

2c

1

2c

Use of HRT among women (%)

31

43c

29

43c

38

35c

37

37c

Body mass index, kg/m2

26.4 (3.8)

26.1 (3.9)

26.3 (3.7)

26.2 (4.0)

26.3 (4.0)

26.3 (3.8)

26.2 (3.9)

26.2 (3.9)

Waist circumference, cm

90 (12)

86 (12)c

90 (12)

86 (12)c

88 (12)

88 (12)c

88 (12)

87 (13)c

Systolic BP, mmHg

137 (18)

133 (18)c

136 (18)

134 (19)c

136 (18)

135 (18)c

136 (18)

135 (19)c

Diastolic BP, mmHg

83 (11)

81 (11)c

83 (11)

82 (11)c

83 (11)

82 (11)c

83 (11)

82 (11)c

Total cholesterol, mmol/L

6.2 (1.2)

6.2 (1.2)

6.2 (1.2)

6.2 (1.2)

6.2 (1.2)

6.1 (1.1)c

6.2 (1.2)

6.2 (1.2)

HDL cholesterol, mmol/L

1.4 (0.4)

1.5 (0.5)c

1.4 (0.4)

1.5 (0.4)c

1.4 (0.4)

1.5 (0.5)c

1.4 (0.4)

1.5 (0.5)c

LDL cholesterol, mmol/L

4.0 (1.0)

3.9 (1.1)c

4.0 (1.0)

3.9 (1.1)

4.0 (1.0)

3.9 (1.0)c

4.0 (1.0)

3.9 (1.0)b

Triglycerides, mmol/L

1.9 (1.2)

1.7 (1.0)c

1.9 (1.1)

1.7 (1.0)c

1.8 (1.1)

1.8 (1.1)c

1.9 (1.1)

1.7 (1.1)c

QRISK2 score, %d

19.4 (13.3)

16.5 (12.4)c

18.7 (13.1)

17.3 (12.7)c

18.8 (13.3)

17.3 (12.7)c

18.6 (13.1)

17.6 (12.9)c

  1. EPIC, European Prospective Investigation of Cancer; FFQ, food frequency questionnaire; BP, blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HRT, hormone replacement therapy; MI, myocardial infarction
  2. aSummary statistics in mean (SD) or percentages for extreme groups of thirds (assigned ensuring approximately equal numbers of observations per group) of each Mediterranean diet scores based on 23,694 participants with baseline FFQ. For each of the Mediterranean diet scores, ordinal scores were assigned to participants (see methods, Additional file 1: Table S1 and S2 for details)
  3. bP < 0.05 and cP < 0.01 for an association between a Mediterranean diet score and each row variable
  4. dPredicts 10 year risk (%) of cardiovascular diseases