Skip to main content

Table 3 Cardiovascular diseases and all-cause mortality, the number of cases and proportion potentially preventable by increasing adherence to the Mediterranean diet: the EPIC-Norfolk studya

From: Prospective association of the Mediterranean diet with cardiovascular disease incidence and mortality and its population impact in a non-Mediterranean population: the EPIC-Norfolk study

 

The whole cohort (n = 23,902)

High risk population (n = 15,767)b

Incidencec

Cases preventablec

PAF% (95 % CI)c

Incidencec

Cases preventablec

PAF% (95 % CI)c

Incident CVD events

 All incident CVD

248.6

9.7

3.9 (1.3–6.5)

334.4

13.0

3.9 (1.1–6.7)

 Incident IHD

98.2

8.4

8.5 (1.9–15.2)

138.3

10.8

7.8 (1.3–14.3)

 Incident stroke

33.8

3.7

10.8 (−1.5 to 23.1)

48.1

4.9

10.2 (−2.1 to 22.6)

 Incident IHD or stroke

120.3

10.2

8.5 (3.1–13.9)

168.9

13.1

7.7 (2.3–13.2)

Mortality events

 All-cause mortality

138.4

7.5

5.4 (1.3–9.5)

191.3

10.9

5.7 (1.6–9.8)

 CVD mortality

43.9

5.5

12.5 (4.5–20.6)

65.0

7.4

11.4 (3.3–19.6)

 IHD mortality

21.1

3.5

16.6 (1.9–31.2)

31.3

4.8

15.4 (0.5–30.3)

 Stroke mortality

13.2

0.7

5.3 (−12.0 to 22.7)

19.6

0.9

4.6 (−13.0 to 22.2)

 IHD or stroke mortality

34.1

4.1

11.9 (1.75–22.0)

50.3

5.4

10.7 (0.48–20.9)

  1. aIncreasing adherence to the top 5 % (95th percentile, or 10.7 out of possible 15 points) of the Mediterranean dietary score based on the dietary pyramid (PyrMDS). See Additional file 1: Table S2 for further details on the scoring criteria for PyrMDS
  2. bHigh risk defined as a QRISK2 score of 10 % or above for 10 year risk of CVD, for whom a pharmacological intervention (statin treatment) is advised in the United Kingdom
  3. cPer 1000 population over 10 years. PAF, indicating proportion of cases attributable to the exposure of interest (low adherence to the Mediterranean diet)
  4. CI, confidence interval; CVD, cardiovascular disease; IHD, ischaemic heart disease; PAF, population attributable fraction