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Table 1 Summary of the proportions of individuals who would receive a primaquine (PQ) dose within the defined therapeutic dosing range of 0.15–0.38 mg base/kg body weight, an underdose (<0.15 mg base/kg), and a supratherapeutic dose (>0.38 mg base/kg)

From: An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia

Age band, years

Weight for age

PQ dose mg base

Underdose

Therapeutic dose

Supratherapeutic dose

PQ mg base/kg

 

1st

median

99th

 

n (%)

n (%)

n (%)

1st

median

99th

0.5–4 (n = 5640)

6.5

11.0

17.1

2.5

89 (1.58)

5,494 (97.41)

57 (1.01)

0.15

0.23

0.38

5–9 (n = 1669)

11.0

17.0

28.8

5

5 (0.3)

1,511 (90.53)

153 (9.17)

0.18

0.29

0.45

10–14 (n = 1508)

19.0

28.0

49.0

7.5

8 (0.53)

1473 (97.68)

27 (1.79)

0.15

0.27

0.39

≥15 (n = 19,321)

36.0

51.1

74.9

15

0

18,489 (95.69)

832 (4.31)

0.20

0.29

0.42

  1. Corresponding mg base/kg doses of PQ are shown for the 1st, 50th (median), and 99th centiles