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Table 1 Clinical characteristics of obese subjects by metabolic syndrome

From: Association of circulating neuregulin 4 with metabolic syndrome in obese adults: a cross-sectional study

Variables

Overall

Metabolic syndrome

Non-metabolic syndrome

P value

Sample size

1212

781

431

 

Age, years

53.3 ± 7.3

54.3 ± 7.2

51.6 ± 7.2

< 0.001

Gender (male), n (%)

347 (28.6)

251 (32.1)

96 (22.3)

< 0.001

BMI, kg/m2

27.1 ± 2.7

27.4 ± 2.8

26.6 ± 2.6

< 0.001

Waist circumference, cm

93.8 ± 7.2

94.7 ± 7.4

92.2 ± 6.6

< 0.001

Current smokers, n (%)

158 (13.0)

104 (13.3)

54 (12.5)

0.445

Systolic BP, mmHg

133.3 ± 17.5

139.2 ± 16.4

122.6 ± 14.2

< 0.001

Diastolic BP, mmHg

79.3 ± 10.6

82.3 ± 10.3

73.7 ± 8.7

< 0.001

Triglycerides, mmol/L

1.6 (1.1–2.3)

1.9 (1.4–2.7)

1.5 (1.1–2.0)

< 0.001

Total cholesterol, mmol/L

5.9 ± 1.1

6.0 ± 1.1

5.7 ± 1.0

< 0.001

LDL- cholesterol, mmol/L

3.7 ± 1.0

3.7 ± 1.0

3.6 ± 0.9

0.533

HDL-cholesterol, mmol/L

1.4 ± 0.3

1.3 ± 0.3

1.5 ± 0.3

< 0.001

Fasting glucose, mmol/L

6.1 ± 1.7

6.5 ± 1.9

5.5 ± 0.9

< 0.001

2-h glucose, mmol/L

9.0 ± 4.0

9.9 ± 4.4

7.2 ± 2.3

< 0.001

HOMA-IR

2.92 (2.10–4.25)

2.81 (2.04–4.04)

2.83 (1.84–3.99)

< 0.001

Serum Nrg4, ng/mL

3.35 (2.47–4.74)

3.24 (2.40–4.52)

3.55 (2.60–5.29)

0.002

Body fat mass, kg

24.0 ± 5.3

24.3 ± 5.4

23.5 ± 5.1

0.013

  1. Data are presented as the mean ± SD or median (interquartile range)
  2. BMI body mass index, HOMA-IR homeostasis model assessment of insulin resistance, Nrg4 Neuregulin 4