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Fig. 3 | BMC Medicine

Fig. 3

From: Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set

Fig. 3

Predicted total mutation load (PTML) correlates with immunotherapy outcomes in melanoma. a Ipilimumab-treated melanoma patients with a low PTML (≤ 100, n= 19) have a poorer overall survival (OS) compared to high PTML patients (> 100, n = 57). Melanoma patients treated with adoptive T-cell therapy using ex vivo expanded tumor infiltrating lymphocytes with a low PTML (n = 8) have shorter progression-free survival (b) and shorter OS (c) compared to high PTML (n = 28) patients (low PTML = red line, high PTML = black line)

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BMC Medicine

ISSN: 1741-7015

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