| SAM N = 131 | Non-SAM N = 266 | P |
---|---|---|---|
Dose planned, n (%) | Â | Â | <0.0001 |
<15Â kg: 20/120Â mg, 1 tablet per intake, 6 tablets, n (%) | 131 (100) | 252 (94.7) | |
≥15 kg: 20/120 mg, 2 tablets per intake, 12 tablets, n (%) | 0 | 14 (5.3) | |
Lumefantrine dose-weight (mg/kg) – mean (SD) | 105.7 (18.6) | 73.2 (18.1) | <0.0001 |
  < 60 mg/kg (theoric efficacy threshold), n (%) | 2 (1.6) | 70 (26.5) | <0.0001 |
  > 100 mg/kg (theoric toxicity threshold), n (%) | 81 (62.8) | 18 (6.8) | <0.0001 |
Early vomiting within 30Â minutes after intake | 49 (37.4) | 55 (20.7) | <0.0001 |
Did not receive the total treatment dosea | 3 (2.3) | 5 (1.9) | 0.784 |