Fig. 2

Kaplan–Meier estimates of survival according to systemic score. a The panel shows the ROC analysis validation for the systemic score. It was performed with an overall performance of the test in terms of the area under the ROC curve (AUC = 0.80 ± 0.06, 95% CI, 0.68–0.91). The sensitivity and specificity were estimated according the Youden criteria, obtaining a systemic score cut-off of 7.0 (sensitivity: 75.00%; specificity: 67.86%). b The panel shows the prognostic impact of systemic score ≥ 7.0. The Kaplan–Meier analysis showed a significant association between a systemic score ≥ 7.0 and mortality (P = 0.0005)