From: Steroid withdrawal after renal transplantation: a retrospective cohort study
 | 3 years after transplantation | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Crude | Matched | |||||||||
Characteristics | n | Steroid withdrawal | n | Steroid maintenance | SMD | n | Steroid withdrawal | n | Steroid maintenance | SMD |
Number of patients | Â | 1272 | Â | 2781 | Â | Â | 884 | Â | 1203 | Â |
Recipient age, years (mean ± SD) | 1272 | 49 (14) | 2781 | 47 (16) | 11% | 884 | 48 (14) | 1203 | 46 (16) | 9% |
Female recipients, n (%) | 1272 | 495 (39) | 2781 | 1012 (36) | 5% | 884 | 348 (39) | 1203 | 457 (38) | 3% |
Diabetes mellitus, n (%) | 750 | 290 (39) | 1828 | 309 (17) | 52% | 465 | 74 (16) | 750 | 100 (13) | 7% |
Arterial hypertension, n (%) | 957 | 814 (85) | 1922 | 1607 (84) | 4% | 655 | 543 (83) | 810 | 675 (83) | 2% |
Living donor, n (%) | 1266 | 180 (14) | 2735 | 323 (12) | 7% | 880 | 117 (13) | 1178 | 144 (12) | 3% |
Donor age, years (mean ± SD) | 1261 | 43 (16) | 2732 | 45 (16) | 10% | 877 | 44 (15) | 1175 | 44 (16) | 4% |
Sum of human leukocyte antigen mismatch (mean ± SD) | 1117 | 3.1 (1.4) | 2435 | 2.6 (1.3) | 38% | 604 | 2.9 (1.3) | 839 | 2.8 (1.3) | 5% |
Immunosuppression, n (%) | 1272 | Â | 2781 | Â | Â | 884 | Â | 1203 | Â | Â |
Cyclosporine A-based regimen | Â | 648 (51) | Â | 1673 (60) | 19% | Â | 493 (56) | Â | 771 (64) | 17% |
Tacrolimus-based regimen | Â | 601 (47) | Â | 1004 (36) | 23% | Â | 376 (43) | Â | 419 (35) | 16% |
Other regimen | Â | 23 (2) | Â | 104 (4) | 11% | Â | 15 (2) | Â | 13 (1) | 6% |