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Table 3 Changes in secondary endpoints

From: The evaluating self-management and educational support in severely obese patients awaiting multidisciplinary bariatric care (EVOLUTION) trial: principal results

Outcome

Sample size

In-person

Web-based

Controls

In-person minus controls

p value*

Web-based minus controls

p value*

In-person minus web-based

p value*

Systolic BP (mm Hg)

568

-2.2 ± 10.0

-0.7 ± 10.3

-2.6 ± 15.4

0.4 ± 12.9

0.79

1.8 ± 13.0

0.20

-1.4 ± 10.1

0.17

Diastolic BP (mm Hg)

569

-1.1 ± 8.6

-1.6 ± 8.6

-1.9 ± 11.8

0.8 ± 10.3

0.56

0.3 ± 10.3

0.82

0.5 ± 8.6

0.57

Total cholesterol (mmol/L)

586

-0.1 ± 0.7

-0.1 ± 0.6

-0.2 ± 0.6

0.1 ± 0.6

0.20

0.02 ± 0.7

0.86

0.1 ± 0.6

0.19

HDL cholesterol (mmol/L)

586

0.01 ± 0.14

0.01 ± 0.16

-0.01 ± 0.13

0.02 ± 0.13

0.11

0.02 ± 0.14

0.18

0.003 ± 0.15

0.8

LDL cholesterol (mmol/L)

576

-0.1 ± 0.4

-0.05 ± 0.4

-0.09 ± 0.4

-0.01 ± 0.4

0.77

0.04 ± 0.4

0.34

-0.05 ± 0.4

0.24

Triglycerides (mmol/L)

586

1.8 ± 1.0

1.8 ± 0.9

1.7 ± 0.8

0.04 ± 0.55

0.50

0.05 ± 0.58

0.38

0.1 ± 0.7

0.15

A1c (%)

573

-0.10 ± 0.40

-0.16 ± 0.80

-0.11 ± 0.50

0.01 ± 0.45

0.79

-0.05 ± 0.64

0.54

0.06 ± 0.63

0.38

EQ-5D VAS score

647

10.3 ± 15.7

11.4 ± 17.3

11.0 ± 17.8

0.7 ± 16.8

0.74

0.4 ± 17.5

0.92

-1.0 ± 16.6

0.52

EQ-5D index score

645

0.03 ± 0.05

0.02 ± 0.04

0.02 ± 0.05

0.01 ± 0.05

0.11

0.001 ± 0.05

0.88

0.006

0.15

SF-12 PC score

639

4.1 ± 7.3

4.9 ± 6.7

3.7 ± 7.2

0.3 ± 7.2

0.63

1.2 ± 6.9

0.08

-0.9 ± 7.0

0.21

SF-12 MC score

639

4.2 ± 8.1

4.1 ± 7.4

4.7 ± 8.8

-0.5 ± 8.5

0.67

-0.6 ± 8.1

0.48

0.06 ± 7.8

0.99

WEL score

649

22.3 ± 31.2

20.8 ± 29.7

22.2 ± 34.6

0.1 ± 32.9

0.90

-1.4 ± 32.1

0.59

1.5 ± 30.4

0.58

Readiness-to-change score

650

-0.08 ± 1.19

-0.14 ± 1.10

-0.07 ± 1.30

0.003 ± 1.30

0.95

0.06 ± 1.20

0.64

0.06 ± 1.13

0.54

PHQ-8 score

632

-2.8 ± 4.4

-3.1 ± 4.2

-3.1 ± 4.8

0.3 ± 4.6

0.63

0.04 ± 4.5

0.93

0.3 ± 4.3

0.54

  1. Numbers are mean ± SD. Baseline-observation-carried-forward imputation
  2. *Adjusted for baseline age, sex and baseline BMI using logistic or linear regression
  3. BP blood pressure, CI confidence interval, EQ EuroQol, HDL high-density lipoprotein, LDL low-density lipoprotein, MC mental component, PC physical component, PHQ Patient Health Questionnaire, SD standard deviation, SF Short Form, VAS visual analogue scale, WEL Weight Efficacy Lifestyle questionnaire