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Fig. 1 | BMC Medicine

Fig. 1

From: Elimination of Hepatitis B: Is It a Mission Possible?

Fig. 1

a Patients with chronic hepatitis B are characterized by a high viral load and antigenaemia, as well as a small number of dysfunctional HBV-specific T-cells. b Failure of combining therapeutic vaccine and nucleos(t)ide analogue treatment could be attributed to T cell exhaustion induced by PD1 and PD-L1 engagement. c Combining anti-PD1, an immune checkpoint inhibitor, with strategy b may be a solution to cure chronic HBV infection

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