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Fig. 2 | BMC Medicine

Fig. 2

From: Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes

Fig. 2

Genetic risk score (GRS) distributions between type 1 diabetes (T1D), type 2 diabetes (T2D), latent autoimmune diabetes in adulthood (LADA), and LADA-restricted cases and controls. The GRS distributions were compared across individuals diagnosed with T1D (n = 1990), T2D (n = 1960), LADA (n = 978), LADA restricted (n = 309), LADA GADA-only (n = 669), and Bone Mineral Density in Childhood Study controls (n = 1057). a Violin plots of the distributions of the GRS calculated using the T1D SNPs for the five groups. A multiple comparison test (Wilcoxon rank sum test) was performed to calculate the significance of pair-wise differences. b Violin plots of the distributions of the GRS calculated using the T2D SNPs for the five groups. A multiple comparison test (Wilcoxon rank sum test) was performed to calculate the significance of pair-wise differences. We include some of the significant P values to highlight key differences. (*** P < 10–5, ** P < 0.0001, * P < 0.05)

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BMC Medicine

ISSN: 1741-7015

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