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Table 1 Distribution of plasma metabolic biomarkers and saturated fatty acid groups in the subcohort (n = 15919) and by sex, age and BMI: EPIC-InterAct study

From: Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study

 

n

Overall Subcohort

Sex

Age (years)

BMI (kg/m2)

   

Men (n = 6002)

Women (n = 9917)

<40 (n = 1524)

40–60 (n = 10919)

≥60 (n = 3476)

<25 (n = 7052)

25–30 (n = 6255)

≥30 (n = 2502)

TC (mmol/L)

15304

5.93 (1.11)

5.92 (1.08)

5.94 (1.13)

5.25 (0.97)

5.92 (1.07)

6.29 (1.13)

5.8 (1.08)

6.05 (1.12)

6.04 (1.13)

HDL-C (mmol/L)

15306

1.50 (0.42)

1.30 (0.36)

1.61 (0.41)

1.48 (0.39)

1.50 (0.42)

1.50 (0.43)

1.63 (0.43)

1.41 (0.38)

1.33 (0.36)

LDL-C (mmol/L)

15125

3.83 (1.00)

3.90 (0.96)

3.79 (1.02)

3.29 (0.88)

3.82 (0.98)

4.11 (1.02)

3.66 (0.98)

3.97 (1.00)

3.96 (0.97)

TC/HDL-Ca

15304

4.00 (3.21–5.00)

4.63 (3.77–5.70)

3.67 (3.00–4.53)

3.50 (2.87–4.42)

4.00 (3.21–5.00)

4.27 (3.47–5.33)

3.53 (2.91–4.4)

4.31 (3.50–5.40)

4.57 (3.73–5.64)

TG (mmol/L)a

15303

1.1 (0.8–1.6)

1.3 (0.9–1.9)

1.0 (0.7–1.4)

0.9 (0.6–1.2)

1.1 (0.8–1.6)

1.3 (0.9–1.8)

0.9 (0.7–1.3)

1.2 (0.9–1.8)

1.4 (0.9–2)

ApoA1 (μmol/L)

15308

54.8 (10.4)

50.2 (8.9)

57.6 (10.2)

53.2 (10.5)

54.8 (10.3)

55.6 (10.4)

56.9 (10.7)

53.5 (9.9)

52.5 (9.5)

ApoB (μmol/L)

15295

1.94 (0.5)

2.03 (0.49)

1.89 (0.5)

1.66 (0.44)

1.94 (0.49)

2.10 (0.5)

1.83 (0.48)

2.02 (0.5)

2.06 (0.49)

ApoB/A1

15295

0.04 (0.01)

0.04 (0.01)

0.03 (0.01)

0.03 (0.01)

0.04 (0.01)

0.04 (0.01)

0.03 (0.01)

0.04 (0.01)

0.04 (0.01)

ALT (μkat/L)a

15274

0.32 (0.23–0.42)

0.38 (0.3–0.52)

0.28 (0.22–0.37)

0.27 (0.2–0.38)

0.32 (0.23–0.43)

0.32 (0.25–0.4)

0.27 (0.22–0.35)

0.33 (0.25–0.45)

0.38 (0.28–0.53)

AST (μkat/L)a

15068

0.45 (0.38–0.52)

0.48 (0.42–0.57)

0.43 (0.37–0.50)

0.40 (0.35–0.47)

0.45 (0.38–0.52)

0.47 (0.42–0.55)

0.43 (0.37–0.5)

0.45 (0.40–0.53)

0.47 (0.40–0.57)

GGT (μkat/L)a

15295

0.33 (0.23–0.53)

0.47 (0.33–0.73)

0.27 (0.22–0.40)

0.27 (0.20–0.37)

0.33 (0.23–0.53)

0.37 (0.27–0.55)

0.28 (0.22–0.42)

0.37 (0.25–0.6)

0.43 (0.28–0.68)

HbA1c (mmol/mol)

15711

36.2 (5.0)

36.4 (5.3)

36.1 (4.8)

33.6 (3.7)

36.0 (5.0)

38.0 (4.8)

35.5 (4.2)

36.4 (4.9)

37.9 (6.6)

CRP (nmol/L)a

15298

10.3 (5.05–22.1)

10.2 (5.24–20.9)

10.4 (4.95–22.8)

7.71 (3.43–18.4)

9.81 (4.86–20.9)

13.4 (6.67–27.2)

6.86 (3.52–14.4)

11.7 (6.29–22.9)

21.1 (10.9–39.6)

Odd-chain SFAs (mol%)

15919

0.63 (0.13)

0.58 (0.13)

0.65 (0.13)

0.63 (0.11)

0.62 (0.14)

0.63 (0.14)

0.65 (0.13)

0.61 (0.13)

0.60 (0.13)

Even-chain SFAs (mol%)

15919

44.6 (1.22)

44.8 (1.12)

44.5 (1.27)

44.2 (1.09)

44.6 (1.21)

44.8 (1.26)

44.4 (1.22)

44.7 (1.20)

44.9 (1.20)

Very-long-chain SFAs (mol%)

15919

0.70 (0.20)

0.69 (0.20)

0.71 (0.20)

0.70 (0.19)

0.70 (0.18)

0.72 (0.24)

0.71 (0.19)

0.70 (0.22)

0.69 (0.16)

  1. aThese metabolic markers were presented as median (interquartile range); all other metabolic markers or SFA groups were presented as mean (SD)
  2. TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglycerides, ApoA1 apolipoprotein A-1, ApoB apolipoprotein B, ALT alanine transaminase, AST aspartate transaminase, GGT gamma glutamyl transferase, HbA1c haemoglobin A1c, CRP C-reactive protein, SFA saturated fatty acid