Variables | Present | Non-present | Unadjusted HR (95% CI) | Adjusted HR (95% CI)a | ||
---|---|---|---|---|---|---|
Number with fracture | Rate per 10,000 person-years (95% CI) | Number with fracture | Rate per 10,000 person-years | |||
PMR | ||||||
Overall | 1689 | 148.05 (141.16–155.28) | 5173 | 115.67 (112.56–118.87) | 1.29 (1.22–1.36) | 1.63 (1.54–1.73) |
Sex | ||||||
Male | 244 | 68.79 (60.68–77.99) | 707 | 52.07 (48.37–56.06) | 1.32 (1.15–1.53) | 1.54 (1.33–1.81) |
Female | 1445 | 183.81 (174.57–193.54) | 4466 | 143.4 (139.25–147.67) | 1.29 (1.22–1.37) | 1.61 (1.52–1.72) |
Age in years | ||||||
40–50 | 16 | 45.58 (27.93–74.41) | 48 | 32.55 (24.53–43.2) | 1.40 (0.81–2.41) | 1.92 (1.01–3.69) |
50–60 | 116 | 81.29 (67.77–97.52) | 264 | 46.04 (40.81–51.94) | 1.78 (1.43–2.2) | 2.23 (1.79–2.79) |
60–70 | 357 | 112.33 (101.26–124.61) | 1018 | 78.56 (73.88–83.53) | 1.44 (1.28–1.62) | 1.85 (1.56–2.10) |
70–80 | 753 | 161.12 (150.01–173.04) | 2555 | 138.51 (133.25–143.99) | 1.17 (1.08–1.26) | 1.51 (1.38–1.64) |
≥ 80 | 447 | 251.34 (229.08–275.75) | 1288 | 210.89 (199.68–222.72) | 1.21 (1.08–1.34) | 1.61 (1.43–1.81) |
GCA | ||||||
Overall | 371 | 147.15 (132.91–162.91) | 1142 | 109.52 (103.35–116.06) | 1.36 (1.22–1.53) | 1.67 (1.49–1.88) |
Sex | ||||||
Male | 49 | 66.62 (50.35–88.15) | 127 | 42.37 (35.61–50.42) | 1.59 (1.15–2.2) | 1.62 (1.17–2.24) |
Female | 322 | 180.31 (161.66–201.12) | 1015 | 136.6 (128.45–145.27) | 1.34 (1.19–1.51) | 1.67 (1.47–1.90) |
Age in years | ||||||
40–50 | 4 | 35.23 (13.22–93.86) | 9 | 18.87 (9.82–36.26) | 1.87 (0.63–5.58) | 1.98 (0.66–5.94) |
50–60 | 18 | 55.2 (34.78–87.61) | 46 | 34.94 (26.17–46.65) | 1.56 (0.9–2.71) | 2.27 (1.25–4.15) |
60–70 | 85 | 112.74 (91.15–139.45) | 257 | 78.19 (69.19–88.36) | 1.49 (1.17–1.89) | 1.79 (1.40–2.30) |
70–80 | 181 | 185.8 (160.61–214.94) | 579 | 141.96 (130.85–154) | 1.34 (1.13–1.57) | 1.65 (1.39–1.95) |
≥ 80 | 83 | 234.75 (189.31–291.1) | 251 | 197.88 (174.85–223.94) | 1.20 (0.93–1.54) | 1.48 (1.13–1.94) |