Table 3 Sensitivity analysis
Sensitivity analysisa | Adjusted mean difference (95% CI ) and ICER | Incremental net benefit: probability intervention is seen as effective with a threshold of: | ||||
|---|---|---|---|---|---|---|
€0 | €10,000 | €30,000 | €50,000 | €100,000 | ||
A. Perspective | ||||||
Costs only related to primary cre and mental health | ||||||
Incremental cost | €–43.61 (–186 to 10) | |||||
Incremental QALY | 0.02(–0.00 to 0.04) | |||||
ICER (cost per QALY gained) | Dominant | 0.9250 | 0.9852 | 0.9808 | 0.9784 | 0.9765 |
All the costs | ||||||
Incremental cost | €–10.32 (–253 to 281) | |||||
Incremental QALY | 0.02(–0.00 to 0.04) | |||||
ICER (cost per QALY gained) | Dominant | 0.537 | 0.8989 | 0.9659 | 0.9724 | 0.9751 |
B. Discount rate (societal perspective) | ||||||
Discount rate: 0% | ||||||
Incremental cost | €–16.19 (–612 to 500) | |||||
Incremental QALY | 0.02 (0.00 to 0.04) | |||||
ICER (cost per QALY gained) | Dominant | 0.5309 | 0.8347 | 0.9413 | 0.9606 | 0.9710 |
Discount rate: 6% | ||||||
Incremental cost | €–16.51 (–618 to 505) | |||||
Incremental QALY | 0.02(–0.00 to 0.04) | |||||
ICER (cost per QALY gained) | Dominant | 0.5316 | 0.8301 | 0.93855 | 0.9584 | 0.9694 |
C. Unit costs (societal perspective) | ||||||
Cost doubled | ||||||
Incremental cost | €–32.76 (–1231 to 1006) | |||||
Incremental QALY (social tariffs) | 0.02(–0.00 to 0.04) | |||||
ICER (cost per QALY gained) | Dominant | 0.5316 | 0.734 | 0.8874 | 0.9301 | 0.9594 |
Costs halved | ||||||
Incremental cost | €–8.19 (–308 to 252) | |||||
Incremental QALY (social tariffs) | 0.02(–0.00 to 0.04) | |||||
ICER (cost per QALY gained) | Dominant | 0.5316 | 0.9140 | 0.9635 | 0.9699 | 0.9734 |
D. Analytical strategy | ||||||
Seemingly unrelated equations (societal perspective) | ||||||
Incremental cost | €–38 (–251 to 174) | |||||
Incremental QALY (social tariffs) | 0.02(–0.00 to 0.04) | |||||
ICER (cost per QALY gained) | Dominant | 0.6383 | 0 .9307 | 0.9711 | 0.9750 | 0.9767 |
Completers analysis (societal perspective)b | ||||||
Incremental cost | €–14.46 (–1217 to 1456) | |||||
Incremental QALY (social tariffs) | 0.02 (0.01 to 0.04) | |||||
ICER (cost per QALY gained) | Dominant | 0.48 | 0.761 | 0.888 | 0.923 | 0.962 |
Models adjusted only by costs or QALYs at baseline (societal perspective) | ||||||
Incremental cost | €118.52 (–909€ to 1497) | |||||
Incremental QALY (social tariffs) | 0.02 (0.01 to 0.04) | |||||
ICER (cost per QALY gained) | €5644/QALY | 0.3864 | 0.7165 | 0.8727 | 0.9218 | 0.9606 |