Skip to main content

Table 4 Median child cause-specific chance-corrected concordance (%) for InSilicoVA and Tariff 2.0

From: Performance of InSilicoVA for assigning causes of death to verbal autopsies: multisite validation study using clinical diagnostic gold standards

   InSilicoVA (Tariff 2.0 training) Tariff 2.0
   No HCE HCE No HCE HCE
PHMRC cause ICD10 Median 95% UI Median 95% UI Median 95% UI Median 95% UI
Diarrhea/dysentery A09 16.0 (14.1, 18.0) 15.1 (12.5, 16.7) 24.6 (24.0, 25.5) 37.0 (36.3, 38.2)
Sepsis A41 −2.8 (−5.0, −1.5) −5.0 (−5.0, −2.7) 12.5 (11.2, 13.5) 14.7 (14.1, 16.0)
Hemorrhagic fever A99 16.0 (14.5, 19.0) 16.0 (13.6, 19.7) 51.5 (51.5, 52.3) 59.6 (59.6, 65.0)
Measles B05 73.8 (70.2, 77.2) 71.9 (67.8, 73.8) 82.5 (82.5, 82.5) 82.5 (82.5, 82.5)
AIDS B24 42.7 (39.1, 47.4) 42.1 (38.2, 47.4) 37.0 (37.0, 37.0) 58.0 (58.0, 58.0)
Malaria B54 47.5 (47.2, 49.8) 49.3 (47.4, 51.3) 41.7 (40.0, 42.1) 57.2 (56.6, 58.8)
Other infectious diseases B99 24.8 (22.8, 27.0) 25.0 (21.4, 27.2) 7.4 (7.4, 10.0) 26.5 (25.9, 27.8)
Other cancers C76 4.3 (−2.8, 6.2) 5.0 (1.8, 8.0) 25.0 (25.0, 30.0) 40.0 (40.0, 40.0)
Meningitis G03 15.0 (12.5, 16.4) 13.3 (11.9, 15.5) 27.3 (25.0, 32.5) 30.0 (26.5, 32.5)
Encephalitis G04 29.9 (26.5, 32.2) 29.8 (24.8, 33.0) 37.0 (37.0, 37.0) 41.7 (37.0, 47.5)
Other cardiovascular diseases I99 7.7 (6.1, 10.4) 10.8 (8.9, 13.9) 11.6 (11.6, 12.5) 33.7 (33.7, 33.7)
Pneumonia J22 16.8 (15.6, 18.3) 16.0 (14.4, 17.5) 7.7 (7.1, 8.1) 9.9 (9.1, 10.8)
Other digestive diseases K92 4.0 (2.4, 5.5) 4.2 (2.3, 6.7) 3.8 (3.8, 3.8) 21.3 (21.3, 21.3)
Other defined causes of child deaths R101 13.0 (11.2, 14.5) 11.2 (8.8, 12.3) 5.5 (4.5, 6.2) 16.9 (16.0, 18.3)
Road traffic V89 90.1 (88.8, 91.2) 89.5 (88.3, 91.2) 90.5 (88.9, 90.9) 90.9 (90.9, 92.5)
Falls W19 54.6 (51.7, 57.6) 55.9 (52.9, 57.9) 73.8 (73.8, 73.8) 73.8 (73.8, 73.8)
Drowning W74 92.5 (90.7, 93.6) 92.5 (91.2, 94.1) 90.0 (89.5, 90.0) 93.8 (92.5, 94.8)
Fires X09 50.9 (47.5, 52.9) 48.4 (47.4, 52.2) 69.1 (69.1, 69.1) 75.3 (73.8, 75.3)
Bite of venomous animal X27 88.5 (86.8, 90.4) 87.7 (85.6, 89.5) 92.5 (92.5, 92.5) 92.5 (92.5, 100.0)
Poisonings X49 37.1 (30.0, 42.3) 40.0 (34.4, 45.3) 47.5 (47.5, 47.5) 73.8 (73.8, 73.8)
Violent death Y09 75.3 (73.7, 76.8) 76.6 (73.7, 79.0) 83.8 (82.5, 83.8) 83.8 (83.8, 83.8)
  1. Table 4 shows the cause-specific chance-corrected concordance for child data for InSilicoVA using an empirical probbase derived from training data mapped to the Tariff 2.0 format. Previously published Tariff 2.0 results are shown for comparison
  2. PHMRC Population Health Metrics Research Consortium, ICD International Classification of Diseases, HCE health care experience, UI uncertainty interval