From: Efficacy and safety of methylene blue in the treatment of malaria: a systematic review
Methodological item | Score for studiesa | ||
---|---|---|---|
Bountogo et al. Burkina Faso (2010) [59] | Meissner et al. Burkina Faso (2006) [60] | Alving (1949) Cited by Baird et al. (2012) [61] | |
Clearly stated aim | 2 | 2 | 1 |
Inclusion of consecutive patients | 2 | 2 | 1 |
Prospective collection of data | 2 | 2 | 0 |
End points appropriate to the aim of the study | 1 | 2 | 1 |
Unbiased assessment of the study end point | 2 | 2 | 0 |
Follow-up period appropriate to the aim of the study | 2 | 2 | 1 |
Loss to follow-up less than 5% | 2 | 2 | 0 |
Prospective calculation of the study size | 2 | 2 | 0 |
Adequate control group | 1 | 2 | 1 |
Contemporary groups | 1 | 1 | 1 |
Baseline equivalence of groups | 1 | 2 | 0 |
Adequate statistical analyses | 2 | 2 | 0 |
Total score | 20 | 23 | 6 |