Variable of interest | HBsAg | Number of cases | Cases/PY (1000) | Multiplicative interaction | Additive interaction | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Stratum-specific HR (95% CI) | p Int-M * | HR (95% CI) | p Int-A † | RERI | Attributable proportion, % | ||||||
HBV infection | Variable of interest | Additive interaction | |||||||||
Daily smoking | |||||||||||
No | Negative | 3166 | 1.09 | 1.00 | 0.030 | 1.00 | 0.030 | 0.56 (0.05, 1.07) | 25.5 (−5.0, 56.1) | 8.2 (− 16.3, 32.6) | 66.3 (32.4, 100.3) |
No | Positive | 108 | 1.20 | 1.20 (0.99, 1.45) | 1.22 (1.00, 1.47) | ||||||
Yes | Negative | 1215 | 1.03 | 1.00 | 1.07 (0.97, 1.18) | ||||||
Yes | Positive | 66 | 1.59 | 1.83 (1.42, 2.34) | 1.85 (1.44, 2.38) | ||||||
Physical inactivity‡ | |||||||||||
No | Negative | 2721 | 0.99 | 1.00 | 0.003 | 1.00 | 0.004 | 0.72 (0.23, 1.21) | 15.9 (−10.6, 42.3) | 5.0 (−18.4, 28.4) | 79.1 (50.5, 107.7) |
No | Positive | 97 | 1.07 | 1.15 (0.94, 1.41) | 1.14 (0.93, 1.40) | ||||||
Yes | Negative | 1660 | 1.24 | 1.00 | 1.05 (0.97, 1.12) | ||||||
Yes | Positive | 77 | 1.90 | 1.80 (1.43, 2.27) | 1.91 (1.52, 2.40) | ||||||
Prevalent diabetes | |||||||||||
No | Negative | 3519 | 0.91 | 1.00 | 0.068 | 1.00 | 0.012 | 2.45 (0.53, 4.38) | 5.4 (0.7, 10.2) | 46.6 (25.9, 67.2) | 48.0 (27.7, 68.3) |
No | Positive | 134 | 1.07 | 1.28 (1.07, 1.52) | 1.28 (1.08, 1.52) | ||||||
Yes | Negative | 862 | 4.11 | 1.00 | 3.38 (3.13, 3.66) | ||||||
Yes | Positive | 40 | 6.54 | 1.77 (1.28, 2.44) | 6.11 (4.47, 8.36) |