Skip to main content
Fig. 3 | BMC Medicine

Fig. 3

From: Epidemiological and genomic determinants of tuberculosis outbreaks in First Nations communities in Canada

Fig. 3

Median joining network of Mycobacterium tuberculosis haplotypes based on single-nucleotide polymorphisms for a RFLP 0.0142 and b RFLP 0.0728. The nodes are colored according to the outbreak and endemic classifications of the isolates. Edges are labeled according to the number of SNPs between the nodes. The size of a node is scaled based on the number of isolates with an identical sequence. The source cases for each outbreak are white (corresponding to group 1a). Secondary cases from each outbreak are green (corresponding to group 1b). Endemic cases occurring prior to the beginning of the outbreak are light purple (corresponding to group 2a). Endemic cases occurring within 1 year of outbreak cases are medium purple. Endemic cases occurring after the outbreak are dark purple (the latter two corresponding to group 2b). Black nodes are intermediate nodes inferred by the median joining algorithm. There are no isolates from endemic cases prior to the outbreak for RFLP 0.0142. Outbreak cases have 0–6 differences from the source case in RFLP 0.0142 and 0–1 differences from the source case in RFLP 0.0728. RFLP restriction fragment-length polymorphism, SNP single-nucleotide polymorphism

Back to article page