Test | Negative result | Sensitivity | Specificity | References and notes | Screening algorithm |
---|
(A) Direct PCR | (B) Culture + PCR | (C) PHE |
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PCR from swab | S | 96% | 99% | Tato et al., 2016 [27] | x | | |
ICHNT PCR | NCP-CREa | 98% | 99% | ICHNT data | | x | x |
Culture (1) | S | 89% | 91% | ICHNT data | | x | x |
Culture (2) | NCP-CRE | 100% | 85% | ICHNT data | | x | x |
PHE PCR | NCP-CREa | 100% | 100% | Assumed optimal | | | x |
- Sensitivity is the probability that the test detects resistance given that the patient carries resistant Enterobacteriaceae. Specificity is the probability of a negative test for resistance given that the patient does not carry resistant bacteria
- aAs both of these PCR tests are on samples that have shown to be culture positive for CRE, they are classified as NCP-CRE if the PCR test for CPE is negative