LC–MS Proteomes | Mean of protein intensity | ||
---|---|---|---|
Fibrosis ≥ 2 (n)a,b | Fibrosis < 2 (n)a,b,c | Percentage collagen ρc,d | |
Protein alpha-1-microglobulin/bikunin preproprotein | 0.170 ± 0.101 | 0.233 ± 0.091** | −0.25* |
Alpha-2-macroglobulin | 0.144 ± 0.144 | 0.060 ± 0.087** | 0.32* |
Apolipoprotein E isoform a | 0.320 ± 0.184 | 0.426 ± 0.219** | −0.24 |
Transthyretin precursor | 0.084 ± 0.056 | 0.053 ± 0.032** | 0.26* |
Vitamin K-dependent protein S preproprotein | 0.057 ± 0.044 | 0.031 ± 0.030* | −0.06 |
Selenoprotein P isoform 2 | 0.013 ± 0.019 | 0.030 ± 0.044* | −0.19 |
Carboxypeptidase B2 isoform 2 preproprotein | 0.025 ± 0.030 | 0.045 ± 0.042* | −0.24 |
Apolipoprotein C-II | 0.115 ± 0.038 | 0.156 ± 0.093* | −0.19 |
Histidine-rich glycoprotein isoform X1 | 0.497 ± 0.252 | 0.619 ± 0.230* | −0.31* |
Apolipoprotein B-100 isoform X1 | 0.250 ± 0.606 | 0.039 ± 0.073* | 0.23 |
Apolipoprotein A-I preproprotein | 0.753 ± 0.372 | 0.582 ± 0.222* | 0.16 |
Inter-alpha trypsin inhib. hvy. ch.H4 isoform 2 | 0.045 ± 0.040 | 0.027 ± 0.030* | 0.05 |
Coagulation factor V | 0.048 ± 0.053 | 0.046 ±0.053 | −0.36** |
Alpha-1-antitrypsin | 0.193 ± 0.192 | 0.121 ± 0.051* | 0.34** |
Platelet basic protein preproprotein | 0.081 ± 0.053 | 0.100 ± 0.044 | −0.33** |
Vitamin D-binding protein isoform 3 | 0.052 ± 0.064 | 0.028 ± 0.037 | 0.28* |
C4b-binding protein alpha chain | 0.107 ± 0.084 | 0.102 ± 0.086 | −0.27* |
Complement C4-A isoform 1 preproprotein | 0.589 ± 0.269 | 0.605 ± 0.212 | − 0.26* |
Alpha-1-acid glycoprotein 1 precursor | 0.090 ± 0.062 | 0.065 ± 0.041 | 0.25* |