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Fig. 3 | BMC Medicine

Fig. 3

From: High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure

Fig. 3

Examples of selection for double-dose artemisinin resistance. Demonstrative parasitemia trends as seen at different time points during the resistance selection process are shown from mice that received a 2-day regimen comprising two doses 24 h apart of (a) 9.6 mg/kg, (b) 38.4 mg/kg, or (c) 80 mg/kg artesunate (i.e., total of 19.2 mg/kg, 86.8 mg/kg, or 160 mg/kg AS per APC). Arrows indicate day of intravenous drug delivery. Results were reproduced in several mice as indicated in Table S2B

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