Dose of Artesunate (mg/kg) | 2.4 | 3.3 | 4 | 15 | 30 | 60 | 120 | 240 |
---|---|---|---|---|---|---|---|---|
Number of APC required to reach resistance | 3 | 2 | 2, 3, 1, 2, 1 | 3, 9, 6, 2 | 1, 2, 4, 5, 3, 4, 2 | 5, 1 | 3, 3, 4, 2, 3, 3, 2, 2, 2, 2, 2 | 4, 1, 7, 1, 2, 1, 2, 1, 1, 1, 1 |
Number of mice with resistance/total attempted | 1/4 | 1/3 | 5/5 | 4/5 | 7/8 | 2/2 | 11/11 | 11/15 |