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Table 2 Treatment and covariate effects on unfavourable outcome for men (N = 974)

From: Gender differences in tuberculosis treatment outcomes: a post hoc analysis of the REMoxTB study

 

r/n

OR (unadjusted), 95% CI

p

aOR (adjusted), 95% CI

p

Treatment

 HRZE

30/326 (33)

  

1.0

 

 2MHRZ/2MHR

55/312 (32)

2.22 (1.36–3.62)

0.001

2.24 (1.37–3.65)

0.001

 2EMRZ/2MR

78/336 (35)

3.31 (2.07–5.29)

< 0.001

3.31 (2.07–5.28)

< 0.001

Age

 ≤ 30 years

58/435

1.0

 

1.0

 

 > 30 years

105/539

1.46 (1.00–2.12)

0.045

1.48 (1.02–2.14)

0.037

BMI

 < 18.5

105/547

1.0

 

1.0

 

 ≥ 18.5

58/427

0.65 (0.45–0.93)

0.020

0.64 (0.44–0.92)

0.017

Race

 Asian

50/311

1.0

   

 Black

70/430

0.85 (0.55–1.32)

0.469

–

–

 Mixed race and Caucasian

43/233

0.97 (0.58–1.61)

0.902

  

Smoking

 Never smoked

39/334

1.0

 

1.0

 

 Ever smoked

124/640

1.61 (1.04–2.49)

0.034

1.60 (1.07–2.40)

0.023

HIV

 Negative

143/922 (95)

1.0

 

1.0

 

 Positive

20/52

4.26 (2.22–8.18)

< 0.001

3.97 (2.12–7.42)

< 0.001

Cavities

 No cavities

16/198

1.0

 

1.0

 

 Cavities

147/776

2.78 (1.59–4.85)

< 0.001

2.78 (1.59–4.84)

< 0.001

  1. r number with unfavourable outcome
  2. n total in category