Frailty, nutrition-related parameters, and mortality across the adult age spectrum

Table 14 Association between nutritional index and mortality across levels of frailty

Nutritional index	Frailty index score
	≤ 0.1	p value	> 0.1 to 0.2	p value	> 0.2 to 0.3	p value	> 0.3	p value
	HR (95%CI)	p value	HR (95%CI)	p value	HR (95%CI)	p value	HR (95%CI)	p value
Nutritional index score (per 0.1 score)	1.15 (0.98, 1.35)	0.082	1.17 (1.06, 1.30)	0.002*	1.20 (1.08, 1.32)	< 0.001*	1.27 (1.16, 1.38)	< 0.001*
Nutritional index score in group
≤ 0.2	1.00		1.00		1.00		1.00
> 0.2 to 0.3	1.26 (0.72, 2.18)	0.420	0.99 (0.64, 1.53)	0.958	1.73 (1.01, 2.97)	0.046*	1.63 (0.91, 2.91)	0.100
> 0.3 to 0.4	1.44 (0.80, 2.59)	0.219	1.35 (0.88, 2.06)	0.164	1.80(1.06, 3.05)	0.029*	2.05 (1.20, 3.52)	0.009*
> 0.4 to 0.5	1.70 (0.88, 3.31)	0.117	2.04 (1.34, 3.11)	0.001*	2.34 (1.36, 4.01)	0.002*	1.92 (1.12, 3.31)	0.019*
> 0.5	1.58 (0.66, 3.76)	0.302	1.49 (0.89, 2.51)	0.130	2.49 (1.42, 4.38)	0.001*	3.09 (1.81, 5.27)	< 0.001*
P for trend across nutritional index group		0.097		0.001*		0.001*		< 0.001*

All analyses were adjusted for age, sex, race, educational level, marital status, employment status, smoking, and study cohort, *p value < 0.05

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