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Table 9 Association between abnormal blood tests and frailty

From: Frailty, nutrition-related parameters, and mortality across the adult age spectrum

Blood tests

Linear regression analysis

β-coefficient (95%CI)

p value

Total lymphocyte count

Low

0.010 (0.005, 0.015)

< 0.001*

Haemoglobin

Low

0.048 (0.042, 0.055)

< 0.001*

High

− 0.003 (− 0.022, 0.017)

0.798

Mean corpuscular volume

Low

0.037 (0.027, 0.046)

< 0.001*

High

0.041 (0.029, 0.053)

< 0.001*

Albumin

Low

0.037 (0.029, 0.046)

< 0.001*

Vitamin A

Low

0.085 (0.030, 0.139)

0.002*

High

0.051 (0.044, 0.059)

< 0.001*

Vitamin C

Low

0.011 (0.003, 0.019)

0.005*

High

− 0.001 (− 0.013, 0.011)

0.845

Vitamin D

Low

0.015 (0.011, 0.019)

< 0.001*

High

− 0.150 (− 0.036, 0.006)

0.160

Pyridoxine

Low

0.015 (0.010, 0.020)

< 0.001*

Folate, RBC

Low

− 0.008 (− 0.017, 0.001)

0.093

Cobalamin

Low

0.006 (− 0.005, 0.018)

0.287

α-carotene

Low

0.023 (0.018, 0.028)

< 0.001*

High

− 0.023 (− 0.030, − 0.017)

< 0.001*

β-carotene

Low

0.025 (0.020, 0.030)

< 0.001*

High

− 0.022 (− 0.028, − 0.016)

< 0.001*

β-cryptoxanthin

Low

0.031 (0.026, 0.036)

< 0.001*

High

− 0.017 (− 0.022, − 0.012)

< 0.001*

Lutein/Zeaxanthin

Low

0.032 (0.028, 0.036)

< 0.001*

High

− 0.018 (− 0.027, − 0.009)

< 0.001*

Lycopene

Low

0.022 (0.017, 0.027)

< 0.001*

High

− 0.008 (− 0.014, − 0.002)

0.014*

Iron, serum

Low

0.021 (0.016, 0.027)

< 0.001*

High

0.001 (− 0.015, 0.016)

0.947

Creatinine

Low

0.008 (0.000, 0.016)

0.048*

High

0.070 (0.062, 0.078)

< 0.001*

Total cholesterol

High

− 0.015 (− 0.019, − 0.011)

< 0.001*

Triglyceride

High

0.017 (0.013, 0.021)

< 0.001*

HDL-c

Low

0.012 (0.008, 0.016)

< 0.001*

LDL-c

High

− 0.018 (− 0.024, − 0.012)

< 0.001*

Glucose

Low

0.014 (0.001, 0.026)

0.029*

High

0.031 (0.027, 0.036)

< 0.001*

Homocysteine

High

0.056 (0.039, 0.073)

< 0.001*

  1. All analyses were adjusted for age, sex, race, energy intake, educational level, marital status, employment status, smoking and study cohort
  2. HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, RBC red blood cell, *p value < 0.05
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BMC Medicine

ISSN: 1741-7015

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