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Table 2 Summary of treatment failure studies

From: Global variation in bacterial strains that cause tuberculosis disease: a systematic review and meta-analysis

Source

Location

Years

No. of patients

Confounders adjusted for

Findings

RR/OR [95% CI]

Parwati et al. [43]

Indonesia

2000–2005

818

Drug resistance, non-adherence, age, diabetes mellitus, and severity of radiological lesions

Lineage 2 Beijing family were associated with treatment failure.

RR 1.94 [1.26, 3.0]

Chatterjee et al. [44]

India

2004–2007

646

Multi-drug resistance

Lineage 2 Beijing family were associated with treatment failure.

OR 3.29 [1.29, 8.14]

Buu et al. [45]

Vietnam

2003–2007

1106

Multi-drug resistance

Lineage 2 Beijing family were not associated with treatment failure.

OR 0.7 [0.3, 2.0]

van der Spuy et al. [46]

South Africa

1993–2004

1737

None (analysis included only drug-susceptible strains)

Lineage 2 Beijing family were not associated with treatment failure.

Not reported (p > 0.05)