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Table 2 Risk of bias of included studies

From: High-throughput, non-invasive prenatal testing for fetal rhesus D status in RhD-negative women: a systematic review and meta-analysis

Study

Risk of bias

Applicability concerns

Patient selection

Index test

Reference standard

Flow and timing

Patient selection

Index test

Reference standard

Akolekar (2011) [19]

High

High

Unclear

Unclear

High

Low

Unclear

Banch-Clausen (2014) [6]

Low

Low

Low

Low

Unclear

Low

Low

Chitty (2014) [16]

Low

Low

Low

Low

Low

Low

Low

Finning (2008) [17]

Low

Low

Low

Low

Low

Low

Low

Grande (2013) [25]

Low

Low

Low

Low

Low

Low

Low

Soothill (2015) [18]

Low

Unclear

Low

Low

Low

Low

Low

Thurik (2015) [7]

Low

High

Low

High

Low

Low

Low

Wikman (2012) [20]

Low

Low

Low

Low

Unclear

High

Low

  1. High: high risk of bias; Low: low risk of bias