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Table 3 Admission, 8 hour and 24 hour biochemistry

From: Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration

 

Plan C

GASTRO slow

Total

Admission laboratory

 N

53

50

103

  Sodium, median (IQR)

139 (132, 149)

143 (137, 156)

142 (136, 154)

   Hyponatremia (< 135 mmol/L), n (%)

16 (30)

8 (16)

24 (23)

   Hypernatremia (> 145 mmol/L), n (%)

15 (28)

23 (46)

38 (37)

   Severe hypernatraemia > 150 mol/L, n (%)

11 (21)

16 (32)

27 (26)

   Hypokalaemia (< 3.5 mmol/L), n (%)

11 (21)

8 (16)

19 (18)

   High creatinine (> 74 mmol/L), n (%)

11 (21)

12 (24)

23 (23)

   High urea (> 6.4 mmol/L), n (%)

26 (49)

26 (52)

52 (50)

  Glucose, median (IQR)

5.4 (4.9, 6.3)

5.3 (4.4, 6.9)

5.4 (4.7, 6.8)

  Lactatea, median (IQR); N

1.2 (1.0, 2.1); 29

1.3 (1.1, 1.7); 27

1.3 (1.0, 1.7); 56

   High lactate > 3 mmol/l, n (%)

4 (14)

0 (0)

4 (7)

At 8 hours

 N

50

52

102

  Sodium, median (IQR)

142 (135, 147)

142 (138, 148)

142 (136, 148)

   Hyponatremia (< 135 mmol/L), n (%)

12 (24)

6 (12)

18 (18)

   Hypernatremia (> 145 mmol/L), n (%)

17 (34)

19 (37)

36 (35)

   Severe hypernatraemia > 150 mol/L, n (%)

7 (14)

10 (19)

17 (17)

At 24 hours

 N

41

45

86

  Sodium, median (IQR)

142 (138, 154)

143 (138, 156)

143 (138, 155)

   Hyponatremia (< 135 mmol/L), n (%)

7 (17)

5 (11)

12 (14)

   Hypernatremia (> 145 mmol/L), n (%)

16 (39)

18 (40)

34 (40)

   Severe hypernatraemia > 150 mol/L, n (%)

12 (29)

16 (36)

28 (33)

  1. aSoroti sites were unable to do lactate tests