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Fig. 3 | BMC Medicine

Fig. 3

From: Next-generation sequencing identifies monogenic diabetes in 16% of patients with late adolescence/adult-onset diabetes selected on a clinical basis: a cross-sectional analysis

Fig. 3

Cluster characteristics in 1495 patients with a clinical suspicion of monogenic diabetes. Among the 1495 patients, unsupervised clustering identified two clusters. Cluster 1 (937 patients) and cluster 2 (558 patients) mainly differed by the initial severity of diabetes as shown by lower frequency of clinical symptoms of diabetes and of insulin therapy and by lower HbA1c values at diabetes diagnosis. There were also more women and more subjects of EuroCaucasian origin in cluster 1. The frequency of monogenic diabetes was higher (23%) in cluster 1 than in cluster 2 (7%), with almost no GCK-MODY cases in cluster 2

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BMC Medicine

ISSN: 1741-7015

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