RA | Ischemic stroke | |||
---|---|---|---|---|
Low IGF1 < 140 ng/ml | High IGF1 | Low IGF1 < 145 ng/ml | High IGF1 | |
n | 96 | 88 | 66 | 66 |
Age, years | 59.0 [51.2–63] | 47.5 p < 0.0001 [34.5–55.3] | 58.5 p = 0.73 [51–66] | 52.7 p = 0.004 [39.8–61.7] |
Serum IGF1, ng/ml | 109.5 [93–127] | 182.5 p < 0.0001 [158–225] | 111.6 p = 0.74 [92–127] | 183 p < 0.0001 [167–223] |
Height, cm | 166 [161–169] | 167 p = 0.041 [163–172] | 163 p = 0.005 [160–167] | 167 p = 0.009 [161–172] |
Systolic BP, mmHg | 135 [120–145] | 121 p = 0.0027 [120–140] | 135 p = 0.70 [120–140] | 130 p = 0.114[120–140] |
Diastolic BP, mmHg | 80 [75–85] | 80 p = 0.023 [70–80] | 80 p = 0.037 [70–80] | 75 p = 0.058 [70–80] |
TC, mmol/L | 5.6 [4.9–6.0] | 5.0 p = 0.0022 [4.1–5.9] | 5.1 p = 0.0004 [4.5–5.8] | 4.8 p = 0.063 [4.3–5.5] |
LDL, mmol/L | 3.4 [2.8–4.0] | 3.0 p = 0.17 [2.3–3.8] | 2.8 p < 0.0001 [2.1–3.50] | 2.6 p = 0.89 [2.30–3.30] |
HDL, mmol/L | 1.8 [1.5–2.2] | 1.7 p = 0.20 [1.5–2.1] | 1.6 p = 0.0002 [1.30–1.90] | 1.5 p = 0.13 [1.10–1.80] |
BMI, kg/m2 | 25.9 [23.1–29.7] | 23.9 p = 0.0014 [21.9–26.7] | 24.0 p = 0.17 [21.8–28.3] | 24.6 p = 0.94 [22.5–28.0] |
T2D, n (%) | 2 (2.1%) | 4 p = 0.39 (4.5%) | 12 p = 0.0004 (19%) | 7 p = 0.23 (9%) |
Current smokers, n (%) | 15 (16%) | 13 p = 0.88 (16%) | 32 p < 0.001 (48%) | 28 p = 0.49 (45%) |
Hypertension*, n (%) | 25 (26%) | 7 p = 0.011 (8%) | 30 p = 0.012 (45%) | 28 p = 0.17 (42%) |