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Table 2 The clinical features corresponding to the three groups

From: Dissecting genetic factors affecting phenylephrine infusion rates during anesthesia: a genome-wide association study employing EHR data

 

Resistant

Intermediate

Sensitive

P value*

No. of Patients

531

2236

1266

/

Sex: female, N (%)

239 (45.0)

1131 (50.6)

761 (60.1)

< 0.0001

Anesthesia type %

 General

421 (79.3)

1806 (80.9)

1068 (84.3)

 

 Spinal

21 (3.9)

99 (4.4)

43 (3.4)

0.0354

 Others

89 (16.8)

331 (14.7)

155 (12.3)

 

Age at surgery (years)

62.4 ± 13.9

59.5 ± 14.7

67.4 ± 12.5

< 0.0001

Body weight (kg)

94.7 ± 27.6

88.6 ± 23.0

85.4 ± 22.1

< 0.0001

Avg. infusion rate (mcg/min)

76.2 ± 22.4

32.1 ± 11.8

32.4 ± 12.3

< 0.0001

Mean SBP (mmHg)

108.0 ± 11.0

105.4 ± 8.7

123.9 ± 10.9

< 0.0001

SD of SBP

15.0 ± 6.4

10.0 ± 3.7

19.9 ± 7.3

< 0.0001

  1. *P value was calculated from chi-square test for categorical variables, and one-way ANOVA for continuous variables. P value < 0.00625 was considered significant