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Fig. 4 | BMC Medicine

Fig. 4

From: Vaccinating children against influenza: overall cost-effective with potential for undesirable outcomes

Fig. 4

The relation between the difference in QALYs and the additional number of seasons with large influenza epidemics after extending the current program with vaccination of children aged 2–16 years at 50% coverage. Results are based on a time-horizon of 20 years. A large epidemic was defined as a season with a symptomatic attack rate larger than 5%. Outcomes are obtained from a probabilistic sensitivity analysis using 1000 simulations. Gray dots represent simulations with an overall QALY gain, while red dots represent simulations with an overall QALY loss. The black line indicates the average QALY difference. Gray and red percentages represent the proportion of simulations with an overall QALY gain and QALY loss out of the total number of simulations with that specific increase of number of seasons with large epidemics

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