From: Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer’s disease
ADNI3 (n = 499) | ADNI2 (n = 210) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Tract | Volume | Length | AxD | RD | MD | FA | Volume | Length | AxD | RD | MD | FA |
FMajor | 0.41 | 0.83 | 0.55 | 0.09 | 0.14 | 0.02 | 0.89 | 0.18 | 0.64 | 0.07 | 0.07 | 0.08 |
Fminor | 0.41 | 0.85 | 0.06 | 4.1 × 10−3 | 0.01 | 0.41 | 0.44 | 0.59 | 0.37 | 0.26 | 0.22 | 0.16 |
L-ATR | 0.73 | 0.86 | 0.04 | 0.16 | 0.08 | 0.90 | 0.30 | 0.81 | 0.63 | 0.54 | 0.52 | 0.65 |
L-CAB** | 0.41 | 0.74 | 2.1 × 10−5 | 1.9 × 10−7 | 3.0 × 10−7 | 0.04 | 0.01 | 0.10 | 2.7 × 10−4† | 9.3 × 10− 7† | 9.2 × 10− 7† | 0.05† |
L-CCG | 0.95 | 0.96 | 0.06 | 0.02 | 0.01 | 0.39 | 0.65 | 0.65 | 0.08 | 0.95 | 0.34 | 0.46 |
L-CST | 0.86 | 0.83 | 0.21 | 0.21 | 0.17 | 0.40 | 0.62 | 0.08 | 0.06 | 0.90 | 0.51 | 0.32 |
L-ILF** | 0.71 | 0.85 | 0.02 | 0.04 | 0.02 | 0.88 | 0.54 | 0.63 | 0.04† | 0.19 | 0.05 | 0.65 |
L-SLFP** | 0.41 | 0.88 | 0.03 | 0.09 | 0.02 | 0.88 | 0.59 | 0.90 | 0.02† | 0.67 | 0.22 | 0.30 |
L-SLFT** | 0.49 | 0.88 | 0.03 | 0.11 | 0.04 | 0.71 | 0.63 | 0.65 | 1.2 × 10−3† | 0.90 | 0.18 | 0.08 |
L-UNC | 0.85 | 0.85 | 0.03 | 1.1 × 10−3 | 2.0 × 10−3 | 0.55 | 0.08 | 0.63 | 0.18 | 0.11 | 0.08 | 0.76 |
R-ATR | 0.90 | 0.87 | 0.02 | 0.10 | 0.05 | 0.75 | 0.05 | 0.65 | 0.72 | 0.46 | 0.51 | 0.63 |
R-CAB** | 0.60 | 0.63 | 4.8 × 10−3 | 1.2 × 10−5 | 2.3 × 10−5 | 0.04 | 0.06 | 0.06 | 1.2 × 10−3† | 4.2 × 10− 3† | 6.6 × 10−4† | 0.54 |
R-CCG | 0.93 | 0.85 | 4.8 × 10−3 | 0.10 | 0.01 | 0.89 | 0.69 | 0.86 | 0.08 | 0.90 | 0.51 | 0.58 |
R-CST | 0.90 | 0.95 | 0.08 | 0.26 | 0.11 | 0.49 | 0.58 | 0.24 | 0.32 | 0.90 | 0.69 | 0.54 |
R-ILF | 0.34 | 0.83 | 0.04 | 0.07 | 0.04 | 0.95 | 0.95 | 0.95 | 0.09 | 0.86 | 0.46 | 0.95 |
R-SLFP | 0.75 | 0.67 | 0.02 | 0.41 | 0.10 | 0.06 | 0.65 | 0.65 | 0.07 | 0.89 | 0.51 | 0.38 |
R-SLFT** | 0.90 | 0.85 | 0.01 | 0.39 | 0.06 | 0.07 | 0.41 | 0.90 | 0.05† | 0.65 | 0.65 | 0.06 |
R-UNC | 0.75 | 0.85 | 0.04 | 1.6 × 10−3 | 4.8 × 10−3 | 0.20 | 0.13 | 0.79 | 0.54 | 0.86 | 0.65 | 0.76 |