Fig. 2

Forest plot (random effects model) of the association between immune-related adverse event development and overall survival. The sizes of the squares indicate the weight of the study. Abbreviations: HR, hazard ratio; irAEs, immune-related adverse events; non-irAEs, non-immune-related adverse events. ^aResults for grade 1–2 immune-related adverse events (irAEs). ^bResults for grade 3–4 irAEs