Table 3 Counts and incidence rates for events of hospitalisation due to infection-related complications for the non-antibiotic users in both the validation and derivation cohorts
| Â | CPRD LRTI, N cases (incidence)# | SAIL LRTI, N cases (incidence)# | CPRD URTI, N cases (incidence)# | SAIL URTI, N cases (incidence)# | CPRD UTI, N cases (incidence)# | SAIL UTI, N cases (incidence)# |
|---|---|---|---|---|---|---|
Total events, N | 1646 | 1777 | 3702 | 7117 | 249 | 319 |
Males | 780 (10.76) | 902 (24.90) | 1783 (1.38) | 3797(7.55) | 92 (3.40) | 121 (11.70) |
Females | 866 (9.89) | 875 (22.64) | 1919 (1.12) | 3320 (5.48) | 157 (1.71) | 198 (5.62) |
Age category | ||||||
 ≤ 5 years | 220 (6.99) | 793 (32.06) | 1131 (1.56) | 4957 (11.41) | 9 (1.07) | 43 (7.66) |
 6–18 | 29 (3.65) | 27 (5.99) | 253 (0.45) | 567 (2.55) | 6 (0.56) | 15 (2.99) |
 18–40 | 79 (3.71) | 56 (6.51) | 502 (0.80) | 469 (2.16) | 7 (0.25) | 13 (1.14) |
 41–60 | 170 (5.33) | 103 (11.90) | 450 (0.81) | 279 (2.32) | 18 (0.79) | 19 (3.17) |
 61–80 | 475 (11.38) | 292 (19.74) | 662 (1.57) | 368 (4.33) | 75 (2.72) | 72 (8.36) |
 Over 80 | 673 (26.15) | 506 (37.27) | 704 (6.52) | 477 (15.74) | 134 (6.27) | 157 (17.47) |
Charlson Comorbidity Index | ||||||
 1—very low | 579 (6.74) | 1152 (22.36) | 2139 (0.98) | 6156 (6.67) | 48 (0.70) | 136 (4.46) |
 2 | 605 (11.19) | 379 (22.54) | 1014 (1.46) | 694 (4.37) | 104 (2.99) | 109 (10.65) |
 3 | 307 (21.07) | 171 (36.67) | 362 (3.61) | 180 (8.68) | 49 (4.48) | 49 (14.47) |
 4 | 108 (27.45) | 50 (37.56) | 130 (5.77) | 59 (11.98) | 37 (11.11) | 17 (16.25) |
 5—very high | 47 (28.58) | 25 (46.26) | 57 (7.37) | 28 (18.03) | 11 (7.96) | 8 (18.72) |
IMD quintile | ||||||
 1—most affluent | 329 (9.73) | 436 (25.36) | 762 (1.09) | 1946 (7.33) | 52 (1.98) | 70 (7.76) |
 2 | 392 (11.33) | 358 (24.39) | 744 (1.11) | 1451 (7.09) | 52 (1.90) | 51 (6.23) |
 3 | 343 (10.73) | 344 (22.53) | 723 (1.23) | 1290 (6.14) | 46 (1.93) | 65 (7.23) |
 4 | 318 (10.68) | 305 (23.61) | 769 (1.36) | 1105 (5.97) | 51 (2.32) | 71 (8.00) |
 5—least affluent | 264 (8.83) | 334 (22.54) | 704 (1.46) | 1325 (5.44) | 48 (2.46) | 62 (5.89) |
Ethnicity | ||||||
 White or unknown | 1578 (10.13) | 1762 (23.80) | 3398 (1.20) | 6954 (6.44) | 244 (2.12) | 317 (7.05) |
 Combined minorities | 68 (15.79) | 15 (18.09) | 304 (1.72) | 163 (5.46) | 5 (1.29) | 2 (3.31) |
Hospitalisation (in previous year) | 161 (23.33) | 143 (35.97) | 236 (4.22) | 320 (13.43) | 38 (6.06) | 51 (20.74) |
Outpatient referral (in previous year) | 1163 (12.08) | 837 (27.07) | 2434 (1.53) | 2832 (7.22) | 194 (2.45) | 162 (7.69) |
Flu vaccination (in previous year) | 920 (14.80) | 553 (25.61) | 1332 (2.21) | 1059 (6.60) | 150 (3.60) | 146 (11.20) |