Skip to main content

Table 1 Characteristics of eligible trials (N = 101)

From: Evidence of unexplained discrepancies between planned and conducted statistical analyses: a review of randomised trials

Characteristic

N (%)

Journal (n, %)

Annals of Internal Medicine

3 (3%)

The BMJ

3 (3%)

JAMA

19 (19%)

Lancet

28 (28%)

NEJM

42 (42%)

PLOS Medicine

6 (6%)

Funding (n, %)

 Pharmaceutical

21 (21%)

 Other for-profit medical company

8 (8%)

 Government

37 (37%)

 Charity

5 (5%)

 Multiple including pharmaceutical/other for-profit medical

4 (4%)

 Multiple excluding pharmaceutical/other for-profit medical

22 (22%)

 Others

4 (4%)

Type of intervention (n, %)

 Pharmacologic

52 (51%)

 Surgical

13 (13%)

 Psychosocial/behavioural/educational

9 (9%)

 Others

24 (24%)

 Multiple types

3 (3%)

Cluster trial (n, %)

14 (14%)

Factorial trial (n, %)

3 (3%)

Crossover trial (n, %)

3 (3%)

Non-inferiority trial (n, %)

20 (20%)

No. of treatment arms (n, %)

 Two

85 (84%)

 Three or more

16 (16%)

Sample size

 Median, IQR

758 (306, 2129)

 Min, max

36, 415357