Characteristic | N (%) |
---|---|
Journal (n, %) | |
Annals of Internal Medicine | 3 (3%) |
The BMJ | 3 (3%) |
JAMA | 19 (19%) |
Lancet | 28 (28%) |
NEJM | 42 (42%) |
PLOS Medicine | 6 (6%) |
Funding (n, %) | |
Pharmaceutical | 21 (21%) |
Other for-profit medical company | 8 (8%) |
Government | 37 (37%) |
Charity | 5 (5%) |
Multiple including pharmaceutical/other for-profit medical | 4 (4%) |
Multiple excluding pharmaceutical/other for-profit medical | 22 (22%) |
Others | 4 (4%) |
Type of intervention (n, %) | |
Pharmacologic | 52 (51%) |
Surgical | 13 (13%) |
Psychosocial/behavioural/educational | 9 (9%) |
Others | 24 (24%) |
Multiple types | 3 (3%) |
Cluster trial (n, %) | 14 (14%) |
Factorial trial (n, %) | 3 (3%) |
Crossover trial (n, %) | 3 (3%) |
Non-inferiority trial (n, %) | 20 (20%) |
No. of treatment arms (n, %) | |
Two | 85 (84%) |
Three or more | 16 (16%) |
Sample size | |
Median, IQR | 758 (306, 2129) |
Min, max | 36, 415357 |