Fig. 3From: Circulating mRNAs are differentially expressed in pregnancies with severe placental insufficiency and at high risk of stillbirthThe association between circulating mRNAs in the maternal circulation and fetal acidemia. Those with preterm fetal growth restriction in the FOX study were examined. Maternal bloods were taken within 2 h of birth and fetal pH (pH < 7.2 is defined as fetal acidemia) taken from the umbilical artery shortly after birth. a The spread of umbilical artery pH concentrations in the FOX cohort. Red dot is the median value. b–d Expression levels of three circulating RNAs. For PTGDR2 p = 0.07. e The receiver operated curve when circulating NRA2, RCBTB2, and PTGDR2 in the maternal circulation are combined to detect fetal acidemia (pH < 7.2). The area under the receiver operated curve (AUC) was 0.74 (95% CI 0.59–0.89). *p < 0.05Back to article page