| In-hospital mortality a | Neurologic deficit at discharge in children with cerebral malariab | Death or readmission 6 months of follow-up c | ||||||
---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | aOR (95% CI) | P | OR (95% CI) | aOR (95% CI) | P | OR (95% CI) | aOR (95% CI) | P | |
Antimalarial class | |||||||||
 Quinine | Reference | Reference |  | Reference | References |  | Reference | Reference |  |
 Artemisinin | 0.51 (0.22, 1.20) | 0.22 (0.07, 0.67) | 0.008 | 0.44 (0.24, 0.81) | 0.28 (0.13, 0.59) | 0.0007 | 2.09 (1.22, 3.58) | 1.24 (0.68, 2.27) | 0.49 |
Antimalarial medication | |||||||||
 Quinine | Reference | Reference |  | Reference | Reference |  | Reference | Reference |  |
 Quinine + Artemether | 0.62 (0.21, 1.83) | 0.28 (0.08, 0.97) | 0.05 | 0.29 (0.13, 0.67) | 0.18 (0.07, 0.48) | 0.0005 | 1.88 (0.93, 3.78) | 1.47 (0.68, 3.17) | 0.33 |
 Artemether | 0.36 (0.05, 2.77) | 0.12 (0.01, 1.49) | 0.10 | 0.79 (0.22, 2.82) | 0.50 (0.12, 2.13) | 0.35 | 5.49 (2.44, 12.4) | 3.88 (1.56, 9.69) | 0.004 |
 Artesunate | 0.45 (0.10, 1.93) | 0.17 (0.02, 1.55) | 0.12 | 0.69 (0.25, 1.94) | 0.51 (0.14, 1.83) | 0.30 | 0.96 (0.36, 2.58) | 0.30 (0.10, 0.90) | 0.03 |