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Table 2 Characteristics of 14 studies included in meta-analyses

From: Association of alcohol consumption with morbidity and mortality in patients with cardiovascular disease: original data and meta-analysis of 48,423 men and women

Source

Country

Dataset

Sex

Study size, No.

Meta-analyses Inclusiona

Follow up, yb

Baseline age, yc

Reference group including former drinkers

Pre-/post-event alcohol assessment

Multiple alcohol measures

Quality assessment score

Primary event

ACM case, No.

CVM case, No.

CVE case, No.

HSE/SHeSs

UK

HSE (1994–2008) / SHeSs (1995, 1998, 2003)

M, F

2802

1257

492

NA

9.5

67.3

Bothd

Post-

No

9

MI/angina, strokee

UK Biobank

UK

Initial assessment visit (2006–2010)

M, F

14,386

1640

631

2950

8.7

61.6

Bothd

Post-

No

9

MI, angina, stroke

Levantesi et al., 2013 [12]

Italy

GISSI study

M, F

11,248

1656

NA

1168

5.7

59.4

Yes

Post-

Yes

7

MI

Pai et al., 2012 [13]

USA

Health Professionals Follow-up Study

M

1818

468

243

NA

Up to 20

Range

40–75

Yes

Both

Yes

7

MI

Rosenbloom et al., 2012 [14]

USA

Onset study

F

1253

441

NA

NA

Up to 10

66.1

Yes

Pre-

No

9

MI

Janszky et al., 2008 [44]

Sweden

SHEEP study

M, F

1332

259

140

NA

8.6

59.4

No

Pre-

No

9

MI

Masunaga et al., 2006 [41]

Japan

Consecutive patients

M

3845

NA

NA

142

1.1

57.2

No

Post-

No

8

MI

Aguilar et al., 2004 [36]

USA, Canada

SAVE trial

M, F

2036

355

284

NA

3.5

59.2

Yes

Both

No

7

MI

Jackson et al., 2003 [37]

USA

Physicians’ Health Study

M

1320

369

267

NA

4.5

67.4

Yes

Post-

No

6

Stroke

de Lorgeril et al., 2002 [43]

France

Lyon Diet Heart Study

M

353

NA

NA

104

4.0

54.0

Yes

Post-

Yes

7

MI

Mukamal et al., 2001 [45]

USA

Onset study

M, F

1913

317

238

NA

3.8

61.8

Yes

Pre-

No

8

MI

Shaper et al., 2000 [46]

UK

British Regional Heart Study

M

596

258

184

NA

12.8

Range

45–64

No

Post-

No

9

MI, angina

Valmadrid et al., 1999 [56]

USA

WESDR

M, F

163

NA

52

NA

Up to 12.3

68.6

No

Post-

No

9

MI/anginae, f

Muntwyler et al., 1998 [38]

USA

Physicians’ Health Study

M

5358

920

NA

NA

5.0

64.1

Yes

Post-

No

6

MI

  1. ACM all-cause mortality, CVE cardiovascular events, CVM cardiovascular mortality, F female, HSE the Health Survey for England, M male, MI myocardial infarction, SHeSs the Scottish Health Survey
  2. aNot applicable (NA) if the study was not included in meta-analysis on the outcome
  3. bData are mean/median unless otherwise specified
  4. cData are mean unless otherwise specified
  5. dFormer drinkers were included only in subgroup meta-analyses on different non-drinking reference group
  6. eResults were not reported separately for angina and MI patients
  7. fOlder-onset diabetic patients with a history of angina or MI