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Table 2 Primary outcome - randomised to host trial

From: Can we achieve better recruitment by providing better information? Meta-analysis of ‘studies within a trial’ (SWATs) of optimised participant information sheets

Study

Optimised

Standard

Odds ratio

95% CI

% weight

CASPER

116 / 5765

113 / 5766

1.027

0.791 to 1.334

27.5

ECLS

180 / 1136

176 / 1126

1.016

0.660 to 1.564

10.1

Healthlines (Depression)

43 / 682

27 / 682

1.630

1.000 to 2.670

7.8

Help Diabetes

183 / 2510

166 / 2370

1.044

0.589 to 1.852

5.7

ISDR

422 / 1666

393 / 1503

0.951

0.752 to 1.201

34.2

REFORM

63 / 2301

62 / 2298

1.010

0.710 to 1.450

14.7

Pooled

1007 / 14,060 (7.2%)

937 / 13,745 (6.8%)

1.034

0.902 to 1.186

100.0

  1. Heterogeneity chi-squared = 3.82, p = 0.576; I2 = 0.0%; estimate of between-study variance = 0.000; test of pooled odds ratio = 1: z = 0.48, p = 0.630
  2. Sensitivity analysis excluding ISDR trial results: pooled odds ratio = 1.08 (95% CI 0.913 to 1.279, p = 0.370); I2 = 0.0%, p = 0.547