Skip to main content
Fig. 3 | BMC Medicine

Fig. 3

From: Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer’s disease and Parkinson’s disease: a large-scale multi-trait association analysis

Fig. 3

GARFIELD enrichment of SNPs with Pmtag < 5 × 10−8 in MTAGLBD. Enrichment in genic regions (a), DHS (hotspots) regions of different tissues (b), chromatin states of different tissues (c), and histone modified regions of different tissues (d). The horizontal axis represents the enrichment odds ratios of each annotation category derived from logistic regression, and the vertical axis shows the corresponding −log10 P values. The dashed line corresponds to the significance threshold of P = 0.05/1005. The size of the dots indicates the number of independent SNPs in a specific annotation. The color of the dots in c and d indicates different tissue types

Back to article page