Fig. 3From: Identification of novel proteins for lacunar stroke by integrating genome-wide association data and human brain proteomesOverlap of significant genes between lacunar stroke and other traits. Overlap between results of the lacunar stroke PWAS and PWAS for other traits. The PWAS used the discovery ROS/MAP proteomic dataset (N = 376) and GWAS summary results. The following outcomes were tested: ischemic stroke (N =60,341), large-artery atherosclerotic stroke (N = 6688), brain microbleeds (N = 3556), neuroticism (N = 390,278), body mass index (BMI; N = 681,275), and waist-to-hip ratio adjusting for BMI (WHRadjBMI; N = 694,649). Significant genes considered for overlap are those with FDR P < 0.05Back to article page