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Fig. 3 | BMC Medicine

Fig. 3

From: Identification of novel proteins for lacunar stroke by integrating genome-wide association data and human brain proteomes

Fig. 3

Overlap of significant genes between lacunar stroke and other traits. Overlap between results of the lacunar stroke PWAS and PWAS for other traits. The PWAS used the discovery ROS/MAP proteomic dataset (N = 376) and GWAS summary results. The following outcomes were tested: ischemic stroke (N =60,341), large-artery atherosclerotic stroke (N = 6688), brain microbleeds (N = 3556), neuroticism (N = 390,278), body mass index (BMI; N = 681,275), and waist-to-hip ratio adjusting for BMI (WHRadjBMI; N = 694,649). Significant genes considered for overlap are those with FDR P < 0.05

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