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Table 1 Demographic baseline characteristicsa,b

From: A digital application and augmented physician rounds reduce postoperative pain and opioid consumption after primary total knee replacement (TKR): a randomized clinical trial

Variable

APP

(N = 24)

DOC

(N = 24)

APP+DOC

(N = 24)

TAU

(N = 24)

p

Demographics

Age — year

65 ± 12

69 ± 9

66 ± 9

71 ± 8

.08

Female sex — no. (%)

14 (58)

14 (58)

14 (58)

14 (58)

 

Clinical knee pain

 Preoperative clinical knee pain without analgesics NRS

6.3 ± 1.6

7.0 ± 1.9

6.6 ± 1.9

6.3 ± 2.7

.63

Missing — no. (%)

1 (4)

0 (0)

0 (0)

1 (4)

 

Acute knee pain

 Preoperative acute knee pain one day prior to surgery NRS

4.3 ± 2.4

3.5 ± 2.6

4.5 ± 2.5

3.16 ± 2.6

.25

Missing — no. (%)

4 (17)

2 (8)

3 (13)

5 (21)

 

Expectation about postoperative pain

 Expected knee pain with analgesics NRS

4.0 ± 2.2

2.9 ± 2.3

4.5 ± 2.8

3.0 ± 2.2

.20

 Expected wound pain with analgesics NRS

3.5 ± 2.6

3.2 ± 3.0

2.4 ± 2.5

2.5 ± 2.4

.39

Missing — no. (%)

1 (4)

0 (0)

0 (0)

0 (0)

 

Self-rated functional capacity

 Subjective functional capacity without analgesics NRS

6.1 ± 2.1

7.0 ± 2.8

6.1 ± 3.0

6.3 ± 2.2

.58

Missing — no. (%)

1 (4)

0 (0)

0 (0)

1 (4)

 

Self-rated physical functional capacity: expectations

 Expected functional capacity with analgesics NRS

4.9 ± 3.0

4.4 ± 3.2

4.6 ± 2.7

4.8 ± 2.6

.96

Missing — no. (%)

1 (4)

1 (4)

1 (4)

0 (0)

 

Questionnaires

 Lequesne Index (questions related to pain, ability to walk, and coping with everyday life)

11.8 ± 3.7

12.3 ± 4.5

13.4 ± 3.7

13.1 ± 3.8

.52

Missing — no. (%)

0 (0)

2 (8)

2 (8)

3 (13)

 

PHQ4 (health questionnaire for patients consisting of the PHQ-2 and GAD-2)

   

 PHQ-2 no. (%) (questions related to depression)

  

.68

  < 3

17 (71)

18 (75)

16 (67)

16 (67)

 

  ≥ 3

5 (21)

3 (13)

5 (21)

2 (8)

 

  Missing — no. (%)

2 (8)

3 (13)

3 (13)

6 (25)

 

 GAD-2 no. (%) (questions related to generalized anxiety)

 

.85

  < 3

21 (88)

19 (79)

17 (71)

18 (75)

 

  ≥ 3

1 (4)

2 (8)

3 (13)

2 (8)

 

  Missing — no. (%)

2 (8)

3 (13)

4 (17)

4 (17)

 

FSS (questions related to pain-related self-instructions)

  Catastrophizing self-instructions

1.4 ± 1.0

1.3 ± 1.2

1.4 ± 1.1

1.3 ± 1.1

.96

  Missing — no. (%)

2 (8)

3 (13)

3 (13)

4 (17)

 

  Active coping self-instructions

2.6 ± 1.3

2.4 ± 1.3

2.4 ± 1.3

2.7 ± 1.2

.83

  Missing — no. (%)

2 (8)

2 (8)

2 (8)

3 (13)

 

 Stanford Expectations of Treatment Scale (SETS)

  SETS positive expectations

2.2 ± 0.8

2.6 ± 0.9

2.1 ± 0.7

2.4 ± 1.1

.38

  Missing — no. (%)

0 (0)

2 (8)

3 (13)

4 (17)

 

  SETS negative expectations

5.0 ± 1.3

4.9 ± 1.4

4.9 ± 1.4

4.5 ± 1.5

.69

  Missing — no. (%)

1 (4)

2 (8)

3 (13)

4 (17)

 

Medication scheme

  Standard

20

20

19

23

 

  Metamizole intolerance

1

1

2

0

 

  Renal insufficiency

3

3

3

1

 

Anesthesia

  General anesthetic (%)

9 (38)

9 (38)

6 (25)

2 (8)

 

  Spinal anesthesia (%)

15 (63)

13 (54)

18 (75)

20 (83)

 

  Missing no. (%)

0 (0)

2 (8)

0 (0)

2 (8)

 
  1. a Baseline characteristics are related to preoperative pain (NRS), postoperative pain expectations (NRS), functional capacity, self-reported disabilities (Lequesne Index), questions related to depression (PHQ-2), generalized anxiety (GAD-2), pain-related self-instructions (FSS), and treatment expectations (SETS)
  2. b Baseline data are based on the full population indicated in the column headings. If data regarding the baseline characteristics was not available for all patients, the missing numbers for these characteristics are presented in the lines labeled “missing.” The characteristics of the patients at baseline were well balanced between all trial groups. Percentages may not total 100 because of rounding. Plus-minus values are standard deviations (SDs)