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  1. Content type: Research article

    Pregnancy is associated with widespread change in metabolism, which may be more marked in obese women. Whether lifestyle interventions in obese pregnant women improve pregnancy metabolic profiles remains unkno...

    Authors: Harriet L. Mills, Nashita Patel, Sara L. White, Dharmintra Pasupathy, Annette L. Briley, Diana L. Santos Ferreira, Paul T. Seed, Scott M. Nelson, Naveed Sattar, Kate Tilling, Lucilla Poston and Deborah A. Lawlor

    Citation: BMC Medicine 2019 17:15

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  2. Content type: Mini Review

    Where should I submit my paper? This is a question that young scientists and trainees frequently ask. In this Commentary, we advise on how to make such a decision whilst balancing the risks and benefits. We ar...

    Authors: Clare Fiala and Eleftherios P. Diamandis

    Citation: BMC Medicine 2019 17:12

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  3. Content type: Research article

    Plasmodium falciparum infections with slow parasite clearance following artemisinin-based therapies are widespread in the Greater Mekong Subregion. A molecular marker of the slow clearance phenotype has been iden...


    Citation: BMC Medicine 2019 17:1

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  4. Content type: Research article

    Naltrexone is an opioid antagonist used in many different conditions, both licensed and unlicensed. It is used at widely varying doses from 3 to 250 mg. The aim of this review was to extensively evaluate the s...

    Authors: Monica Bolton, Alex Hodkinson, Shivani Boda, Alan Mould, Maria Panagioti, Sarah Rhodes, Lisa Riste and Harm van Marwijk

    Citation: BMC Medicine 2019 17:10

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    The Commentary to this article has been published in BMC Medicine 2019 17:30

  5. Content type: Research article

    Excessive gestational weight gain (GWG) leads to obstetric complications, maternal postpartum weight retention and an increased risk of offspring obesity. The GeliS study examines the effect of a lifestyle int...

    Authors: Julia Kunath, Julia Günther, Kathrin Rauh, Julia Hoffmann, Lynne Stecher, Eva Rosenfeld, Luzia Kick, Kurt Ulm and Hans Hauner

    Citation: BMC Medicine 2019 17:5

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  6. Content type: Research article

    Recently, studies have examined the underlying patient and practice factors for missed appointments, but less is known about the impact on patient health. People with one or more long-term conditions who fail ...

    Authors: Ross McQueenie, David A. Ellis, Alex McConnachie, Philip Wilson and Andrea E. Williamson

    Citation: BMC Medicine 2019 17:2

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  7. Content type: Research article

    Conflicting results regarding the impact of repeated vaccination on influenza vaccine effectiveness (VE) may cause confusion regarding the benefits of receiving the current season’s vaccine.

    Authors: Lauren C. Ramsay, Sarah A. Buchan, Robert G. Stirling, Benjamin J. Cowling, Shuo Feng, Jeffrey C. Kwong and Bryna F. Warshawsky

    Citation: BMC Medicine 2019 17:9

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  8. Content type: Research article

    The Opti-HER HEART trial aimed to optimize activity while minimizing cardiac risk by combining trastuzumab, pertuzumab, and paclitaxel with non-pegylated liposomal doxorubicin in the treatment of HER2-positive...

    Authors: Joaquín Gavilá, Mafalda Oliveira, Tomás Pascual, Jose Perez-Garcia, Xavier Gonzàlez, Jordi Canes, Laia Paré, Isabel Calvo, Eva Ciruelos, Montserrat Muñoz, Juan A. Virizuela, Isabel Ruiz, Raquel Andrés, Antonia Perelló, Jerónimo Martínez, Serafín Morales…

    Citation: BMC Medicine 2019 17:8

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  9. Content type: Research article

    Knowledge of HIV-1 molecular transmission clusters (MTCs) is important, especially in large-scale datasets, for designing prevention programmes and public health intervention strategies. We used a large-scale ...

    Authors: Dimitrios Paraskevis, Apostolos Beloukas, Kostantinos Stasinos, Nikos Pantazis, Carmen de Mendoza, Norbert Bannert, Laurence Meyer, Robert Zangerle, John Gill, Maria Prins, Antonella d’Arminio Montforte, Anne-Marte Bakken Kran, Kholoud Porter and Giota Touloumi

    Citation: BMC Medicine 2019 17:4

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  10. Content type: Research article

    Risk stratification and management of acute myocardial infarction patients continue to be challenging despite considerable efforts made in the last decades by many clinicians and researchers. The aim of this s...

    Authors: Alessia Vignoli, Leonardo Tenori, Betti Giusti, Panteleimon G. Takis, Serafina Valente, Nazario Carrabba, Daniela Balzi, Alessandro Barchielli, Niccolò Marchionni, Gian Franco Gensini, Rossella Marcucci, Claudio Luchinat and Anna Maria Gori

    Citation: BMC Medicine 2019 17:3

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  11. Content type: Correspondence

    The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that ...

    Authors: Marc L. Molendijk, Eiko I. Fried and Willem Van der Does

    Citation: BMC Medicine 2018 16:243

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    The original article was published in BMC Medicine 2017 15:23

  12. Content type: Correction

    The original article [1] did not contain comprehensive information regarding two authors’ affiliations that may be considered a potential competing interest.

    Authors: Stewart T. Chang, Violet N. Chihota, Katherine L. Fielding, Alison D. Grant, Rein M. Houben, Richard G. White, Gavin J. Churchyard, Philip A. Eckhoff and Bradley G. Wagner

    Citation: BMC Medicine 2018 16:242

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    The original article was published in BMC Medicine 2018 16:52

  13. Content type: Correction

    The original article [1] contained an error in the presentation of Figure 1; this error has now been rectified and Figure 1 is now presented correctly.

    Authors: Amy Wesolowski, Aimee R. Taylor, Hsiao-Han Chang, Robert Verity, Sofonias Tessema, Jeffrey A. Bailey, T. Alex Perkins, Daniel E. Neafsey, Bryan Greenhouse and Caroline O. Buckee

    Citation: BMC Medicine 2018 16:241

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    The original article was published in BMC Medicine 2018 16:190

  14. Content type: Correspondence

    The SMILES trial was the first intervention study to test dietary improvement as a treatment strategy for depression. Molendijk et al. propose that expectation bias and difficulties with blinding might account...

    Authors: Felice N. Jacka, Adrienne O’Neil, Catherine Itsiopoulos, Rachelle Opie, Sue Cotton, Mohammadreza Mohebbi, David Castle, Sarah Dash, Cathrine Mihalopoulos, Mary Lou Chatterton, Laima Brazionis, Olivia M. Dean, Allison Hodge and Michael Berk

    Citation: BMC Medicine 2018 16:237

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    The original article was published in BMC Medicine 2017 15:23

  15. Content type: Correction

    The original version of this paper [1] did not specify that a website was used in the final year of recruitment, in addition to the other stated recruitment methods.

    Authors: Felice N. Jacka, Adrienne O’Neil, Rachelle Opie, Catherine Itsiopoulos, Sue Cotton, Mohammedreza Mohebbi, David Castle, Sarah Dash, Cathrine Mihalopoulos, Mary Lou Chatterton, Laima Brazionis, Olivia M. Dean, Allison M. Hodge and Michael Berk

    Citation: BMC Medicine 2018 16:236

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    The original article was published in BMC Medicine 2017 15:23

  16. Content type: Research article

    The UK’s National Health Service (NHS) is currently subject to unprecedented financial strain. The identification of unnecessary healthcare resource use has been suggested to reduce spending. However, there is...

    Authors: Jack W. O’Sullivan, Sarah Stevens, Jason Oke, F. D. Richard Hobbs, Chris Salisbury, Paul Little, Ben Goldacre, Clare Bankhead, Jeffrey K. Aronson, Carl Heneghan and Rafael Perera

    Citation: BMC Medicine 2018 16:229

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  17. Content type: Commentary

    Mass drug administration (MDA) of antimalarials has re-emerged as a recommended tool for interrupting malaria transmission, but evidence from low endemicity settings is scarce. A trial in Zanzibar found that t...

    Authors: Manuel W. Hetzel and Blaise Genton

    Citation: BMC Medicine 2018 16:239

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    The original article was published in BMC Medicine 2018 16:215

  18. Content type: Commentary

    de Boer and colleagues present a cost-effectiveness analysis based in the Netherlands of two vaccines available for the prevention of herpes zoster. Zostavax® was the first vaccine available for the prevention...

    Authors: Chester B. Good, Natasha Parekh and Inmaculada Hernandez

    Citation: BMC Medicine 2018 16:238

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    The original article was published in BMC Medicine 2018 16:228

  19. Content type: Research article

    The World Health Organization has set an ambitious goal of eliminating viral hepatitis as a major public health threat by 2030. However, in sub-Saharan Africa, antiviral treatment of chronic hepatitis B (CHB) ...

    Authors: Hailemichael Desalegn, Hanna Aberra, Nega Berhe, Bitsatab Mekasha, Kathrine Stene-Johansen, Henrik Krarup, Andre Puntervold Pereira, Svein Gunnar Gundersen and Asgeir Johannessen

    Citation: BMC Medicine 2018 16:234

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  20. Content type: Correction

    The original article [1] contained an error whereby Table 5 within the Appendix is presented incorrectly. This error has now been corrected and Table 5 is presented appropriately.

    Authors: Kulapong Jayanama, Olga Theou, Joanna M. Blodgett, Leah Cahill and Kenneth Rockwood

    Citation: BMC Medicine 2018 16:235

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    The original article was published in BMC Medicine 2018 16:188

  21. Content type: Editorial

    There is clear guidance on the responsibilities of editors to ensure that the research they publish is of the highest possible quality. Poor reporting is unethical and directly impacts patient care. Reporting ...

    Authors: David Moher

    Citation: BMC Medicine 2018 16:233

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  22. Content type: Review

    Lifestyle factors conferring increased diabetes risk are associated with elevated basal insulin levels (hyperinsulinaemia). The latter predicts later obesity in children and adolescents.

    Authors: Hubert Kolb, Michael Stumvoll, Werner Kramer, Kerstin Kempf and Stephan Martin

    Citation: BMC Medicine 2018 16:232

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  23. Content type: Research article

    As part of a national programme to tackle ethnic inequalities, we conducted a systematic review and meta-analysis of research on ethnic inequalities in pathways to care for adults with psychosis living in Engl...

    Authors: Kristoffer Halvorsrud, James Nazroo, Michaela Otis, Eva Brown Hajdukova and Kamaldeep Bhui

    Citation: BMC Medicine 2018 16:223

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    The Commentary to this article has been published in BMC Medicine 2018 16:240

  24. Content type: Research article

    Cognitive spectrum disorders (CSDs) are common in hospitalised older adults and associated with adverse outcomes. Their association with the maintenance of independent living has not been established. The aim ...

    Authors: Jennifer K. Burton, Bruce Guthrie, Simona M. Hapca, Vera Cvoro, Peter T. Donnan and Emma L. Reynish

    Citation: BMC Medicine 2018 16:231

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  25. Content type: Research article

    Mass drug administration (MDA) has the potential to interrupt malaria transmission and has been suggested as a tool for malaria elimination in low-endemic settings. This study aimed to determine the effectiven...

    Authors: Ulrika Morris, Mwinyi I. Msellem, Humphrey Mkali, Atiqul Islam, Berit Aydin-Schmidt, Irina Jovel, Shija Joseph Shija, Mwinyi Khamis, Safia Mohammed Ali, Lamija Hodzic, Ellinor Magnusson, Eugenie Poirot, Adam Bennett, Michael C. Sachs, Joel Tarning, Andreas Mårtensson…

    Citation: BMC Medicine 2018 16:215

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    The Commentary to this article has been published in BMC Medicine 2018 16:239

  26. Content type: Research article

    The predictive validity of postgraduate examinations, such as MRCGP and MRCP(UK) in the UK, is hard to assess, particularly for clinically relevant outcomes. The sanctions imposed on doctors by the UK’s Genera...

    Authors: Richard Wakeford, Kasia Ludka, Katherine Woolf and I. C. McManus

    Citation: BMC Medicine 2018 16:230

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  27. Content type: Research article

    The newly registered adjuvanted herpes zoster subunit vaccine (HZ/su) has a higher efficacy than the available live-attenuated vaccine (ZVL). National decision-makers soon need to decide whether to introduce H...

    Authors: Pieter T. de Boer, Alies van Lier, Hester de Melker, Albert J. M. van Wijck, Jan C. Wilschut, Albert Jan van Hoek and Maarten J. Postma

    Citation: BMC Medicine 2018 16:228

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    The Commentary to this article has been published in BMC Medicine 2018 16:238

  28. Content type: Research article

    Emerging evidence suggests intensity of perinatal care influences survival for extremely preterm babies. We evaluated the effect of differences in perinatal care intensity between centres on sensorimotor morbi...

    Authors: Andrei S. Morgan, Laurence Foix L’Helias, Caroline Diguisto, Laetitia Marchand-Martin, Monique Kaminski, Babak Khoshnood, Jennifer Zeitlin, Gérard Bréart, Xavier Durrmeyer, François Goffinet and Pierre-Yves Ancel

    Citation: BMC Medicine 2018 16:227

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  29. Content type: Commentary

    Malaria transmission is highly heterogeneous through time and space, and mapping of this heterogeneity is necessary to better understand local dynamics. New targeted policies are needed as numerous countries h...

    Authors: Jordi Landier, Stanislas Rebaudet, Renaud Piarroux and Jean Gaudart

    Citation: BMC Medicine 2018 16:226

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    The original article was published in Malaria Journal 2018 17:340

  30. Content type: Opinion

    Health-related apps have great potential to enhance health and prevent disease globally, but their quality currently varies too much for clinicians to feel confident about recommending them to patients. The ma...

    Authors: Jeremy C. Wyatt

    Citation: BMC Medicine 2018 16:225

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    The Correction to this article has been published in BMC Medicine 2019 17:144

  31. Content type: Research article

    Previous evidence indicates that sauna bathing is related to a reduced risk of fatal cardiovascular disease (CVD) events in men. The aim of this study was to investigate the relationship between sauna habits a...

    Authors: Tanjaniina Laukkanen, Setor K. Kunutsor, Hassan Khan, Peter Willeit, Francesco Zaccardi and Jari A. Laukkanen

    Citation: BMC Medicine 2018 16:219

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  32. Content type: Research article

    Birth weight and early child growth are important predictors of long-term cardiometabolic disease risk, in line with the Developmental Origins of Health and Disease hypothesis. As human assisted reproductive t...

    Authors: Mark Hann, Stephen A. Roberts, Stephen W. D’Souza, Peter Clayton, Nick Macklon and Daniel R. Brison

    Citation: BMC Medicine 2018 16:224

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  33. Content type: Research article

    Plasmodium ovale spp. and P. malariae cause illness in endemic regions and returning travellers. Far less is known about these species than P. falciparum and P. vivax.

    Authors: Laura E. B. Nabarro, Debbie Nolder, Claire Broderick, Behzad Nadjm, Valerie Smith, Marie Blaze, Anna M. Checkley, Peter L. Chiodini, Colin J. Sutherland and Christopher J. M. Whitty

    Citation: BMC Medicine 2018 16:218

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  34. Content type: Commentary

    Understanding the long-term health impacts of the early-life exposome requires the characterization and assimilation of multi ‘omics’ data to ultimately link molecular changes to exposures. In this way, marker...

    Authors: Alicia DiBattista and Pranesh Chakraborty

    Citation: BMC Medicine 2018 16:222

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    The original article was published in BMC Medicine 2018 16:202

  35. Content type: Editorial

    The past 15 years have seen the emergence of a new paradigm in medical research, namely of people living with medical conditions (whether patients, parents, or caregivers) using digital tools to conduct N-of-1...

    Authors: Paul Wicks

    Citation: BMC Medicine 2018 16:217

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  36. Content type: Editorial

    Pancreatic cancer is the fourth leading cause of cancer-related death in the United States, with increasing incidence. The mortality rate of pancreatic cancer is rising rapidly, and is projected to be the seco...

    Authors: Huiyun Zhu, Tuo Li, Yiqi Du and Min Li

    Citation: BMC Medicine 2018 16:214

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  37. Content type: Commentary

    Improving clinical outcomes and quality of care in diseases such as sepsis, which are heterogeneous in their presenting signs and symptoms, is a challenge. One approach is to utilise the Functional Analysis Re...

    Authors: Damian Roland

    Citation: BMC Medicine 2018 16:213

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    The original article was published in BMC Medicine 2018 16:174

  38. Content type: Guideline

    Adequate reporting of adaptive designs (ADs) maximises their potential benefits in the conduct of clinical trials. Transparent reporting can help address some obstacles and concerns relating to the use of ADs....

    Authors: Munyaradzi Dimairo, Elizabeth Coates, Philip Pallmann, Susan Todd, Steven A. Julious, Thomas Jaki, James Wason, Adrian P. Mander, Christopher J. Weir, Franz Koenig, Marc K. Walton, Katie Biggs, Jon Nicholl, Toshimitsu Hamasaki, Michael A. Proschan, John A. Scott…

    Citation: BMC Medicine 2018 16:210

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  39. Content type: Research article

    It is presumed that pharmacological and non-pharmacological treatment of prenatal common mental disorders can mitigate associated adverse effects in offspring, yet strong evidence for the prophylactic benefits...

    Authors: Marlies E. Brouwer, Alishia D. Williams, Sam E. van Grinsven, Pim Cuijpers, Mijke P. Lambregtse-van den Berg, Huibert Burger and Claudi L. H. Bockting

    Citation: BMC Medicine 2018 16:208

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  40. Content type: Commentary

    Spatial epidemiology is a rapidly advancing field, pushing our abilities to measure, monitor and map pathogens at increasingly finer spatiotemporal scales. However, these scales often do not align with the abi...

    Authors: Andrew J. Tatem

    Citation: BMC Medicine 2018 16:209

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  41. Content type: Research article

    Concerns have been raised that observing other people using e-cigarettes may undermine motivation to quit by renormalising smoking. This study aimed to explore associations between regular exposure to other pe...

    Authors: Sarah E. Jackson, Emma Beard, Susan Michie, Lion Shahab, Tobias Raupach, Robert West and Jamie Brown

    Citation: BMC Medicine 2018 16:206

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  42. Content type: Research article

    In 2005, the FDA cautioned that exposure to paroxetine, a selective serotonin reuptake inhibitor (SSRI), during the first trimester of pregnancy may increase the risk of cardiac malformations. Since then, the ...

    Authors: Shan-Yan Gao, Qi-Jun Wu, Ce Sun, Tie-Ning Zhang, Zi-Qi Shen, Cai-Xia Liu, Ting-Ting Gong, Xin Xu, Chao Ji, Dong-Hui Huang, Qing Chang and Yu-Hong Zhao

    Citation: BMC Medicine 2018 16:205

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