Skip to main content

Articles

Page 5 of 86

  1. High-power short-duration (HPSD) ablation strategy has emerged as a popular approach for treating atrial fibrillation (AF), with shorter ablation time. The utilized Smart Touch Surround Flow (STSF) catheter, w...

    Authors: Wei-Jie Chen, Chun-Xia Gan, Yang-Wei Cai, Yang-Yang Liu, Pei-Lin Xiao, Li-Li Zou, Qing-Song Xiong, Fang Qin, Xie-Xin Tao, Ran Li, Hua-An Du, Zeng-Zhang Liu, Yue-Hui Yin and Zhi-Yu Ling
    Citation: BMC Medicine 2023 21:461
  2. AD16 is a Class 1.1 new drug candidate for Alzheimer’s disease (AD), which has demonstrated potential benefits in AD by reducing neuroinflammation in preclinical studies. Herein, the pharmacokinetics (PK), saf...

    Authors: Daizhuang Peng, Sumei Xu, Ting Zou, Yahui Wang, Wenjuan Ouyang, Yalan Zhang, Chengmei Dong, Dai Li, Jie Guo, Qiuying Shen, Xiaolei Hu, Wenzhi Zhou, Xiaomin Li and Qun Qin
    Citation: BMC Medicine 2023 21:459
  3. Selective fetal growth restriction (sFGR) is an extreme complication that significantly increases the risk of perinatal mortality and long-term adverse neurological outcomes in offspring, affecting approximate...

    Authors: Nana Huang, Wei Chen, Hai Jiang, Jing Yang, Youzhen Zhang, Huifeng Shi, Ying Wang, Pengbo Yuan, Jie Qiao, Yuan Wei and Yangyu Zhao
    Citation: BMC Medicine 2023 21:455
  4. The progression of sleep disturbances remains unclear in patients with early multiple system atrophy (MSA). We aimed to explore the frequency, severity, and coexistence of 2-year longitudinal changes of sleep ...

    Authors: Lingyu Zhang, Yanbing Hou, Chunyu Li, Qianqian Wei, Ruwei Ou, Kuncheng Liu, Junyu Lin, Tianmi Yang, Yi Xiao, Qirui Jiang, Bi Zhao and Huifang Shang
    Citation: BMC Medicine 2023 21:454
  5. The epididymis is crucial for post-testicular sperm development which is termed sperm maturation. During this process, fertilizing ability is acquired through the epididymis-sperm communication via exchange of...

    Authors: Zhuoyao Ma, Jinyu Li, Li Fu, Rong Fu, Ningyuan Tang, Yanmei Quan, Zhixiang Xin, Zhide Ding and Yue Liu
    Citation: BMC Medicine 2023 21:453
  6. Emerging research suggests that attention-deficit/hyperactivity disorder (ADHD) increases the risk for cardiovascular (CVDs) and metabolic disorders (i.e., cardiometabolic disorders) in adulthood. Yet, availab...

    Authors: Maja Dobrosavljevic, Ralf Kuja-Halkola, Lin Li, Zheng Chang, Henrik Larsson and Ebba Du Rietz
    Citation: BMC Medicine 2023 21:452
  7. Widely adopted criteria suggest using either low handgrip strength or poor chair stand performance to identify probable sarcopenia. However, there are limited direct comparisons of these measures in relation t...

    Authors: Jonas Johansson, Sameline Grimsgaard, Bjørn Heine Strand, Avan A. Sayer and Rachel Cooper
    Citation: BMC Medicine 2023 21:451
  8. Leveraging a large nationwide study of Icelandic women, we aimed to narrow the evidence gap around female attention-deficit/hyperactivity disorder (ADHD) and cardiometabolic comorbidities by determining the pr...

    Authors: Unnur Jakobsdottir Smari, Unnur Anna Valdimarsdottir, Thor Aspelund, Arna Hauksdottir, Edda Bjork Thordardottir, Catharina A. Hartman, Pontus Andell, Henrik Larsson and Helga Zoega
    Citation: BMC Medicine 2023 21:450
  9. The immunologic milieu at the maternal–fetal interface has profound effects on propelling the development of the fetal brain. However, accessible epidemiological studies concerning the association between plac...

    Authors: Jixing Zhou, Juan Tong, Xue Ru, Yuzhu Teng, Menglong Geng, Shuangqin Yan, Fangbiao Tao and Kun Huang
    Citation: BMC Medicine 2023 21:449
  10. We test a novel ‘weight scarring’ hypothesis which suggests that past obesity is associated with impairments in current psychological well-being and this increases risk of negative physical health outcomes ass...

    Authors: I Gusti Ngurah Edi Putra, Michael Daly, Angelina Sutin, Andrew Steptoe and Eric Robinson
    Citation: BMC Medicine 2023 21:448
  11. Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are closely related and mutually contribute to the disease’s development. There are many treatment options available to patients. We...

    Authors: Manjun Deng, Yonghao Wen, JingXin Yan, Yichen Fan, Zhixin Wang, Ruixia Zhang, Li Ren, Yinggui Ba, Haijiu Wang, Qian Lu and Haining Fan
    Citation: BMC Medicine 2023 21:447
  12. Vulnerable older adults living with Alzheimer’s disease or Alzheimer’s disease and related dementia (AD/ADRD) and chronic pain generally receive fewer pain medications than individuals without AD/ADRD, especia...

    Authors: Ulrike Muench, Kyung Mi Kim, Zachary Zimmer and Todd B. Monroe
    Citation: BMC Medicine 2023 21:446
  13. Acquired brain injury (ABI) is linked to increased depression risk. Existing therapies for depression in ABI (e.g., cognitive behavioural therapy) have mixed efficacy. Behavioural activation (BA), an intervent...

    Authors: Andrea Kusec, Fionnuala C. Murphy, Polly V. Peers, Ron Bennett, Estela Carmona, Aleksandra Korbacz, Cara Lawrence, Emma Cameron, Andrew Bateman, Peter Watson, Judith Allanson, Pieter duToit and Tom Manly
    Citation: BMC Medicine 2023 21:445
  14. Excess energy intake can lead to metabolic dysfunction-associated steatotic liver disease (MASLD), but the relationship between dietary carbohydrate intake and liver fat content remains unclear. This study aim...

    Authors: Josefina Orliacq, Aurora Pérez-Cornago, Siôn A Parry, Rebecca K Kelly, Dimitrios A Koutoukidis and Jennifer L Carter
    Citation: BMC Medicine 2023 21:444
  15. Metabolite signatures of long-term alcohol consumption are lacking. To better understand the molecular basis linking alcohol drinking and cardiovascular disease (CVD), we investigated circulating metabolites a...

    Authors: Yi Li, Mengyao Wang, Xue Liu, Jian Rong, Patricia Emogene Miller, Roby Joehanes, Tianxiao Huan, Xiuqing Guo, Jerome I. Rotter, Jennifer A. Smith, Bing Yu, Matthew Nayor, Daniel Levy, Chunyu Liu and Jiantao Ma
    Citation: BMC Medicine 2023 21:443
  16. There is growing evidence that substituting animal-based with plant-based foods is associated with a lower risk of cardiovascular diseases (CVD), type 2 diabetes (T2D), and all-cause mortality. Our aim was to ...

    Authors: Manuela Neuenschwander, Julia Stadelmaier, Julian Eble, Kathrin Grummich, Edyta Szczerba, Eva Kiesswetter, Sabrina Schlesinger and Lukas Schwingshackl
    Citation: BMC Medicine 2023 21:404

    The Comment to this article has been published in BMC Global and Public Health 2024 2:3

  17. Waist-to-height ratio (WHtR) has been proposed as a simple and effective screening tool for assessing central obesity and cardiometabolic risk in both adult and pediatric populations. However, evidence suggest...

    Authors: Xin’nan Zong, Roya Kelishadi, Young Mi Hong, Peter Schwandt, Tandi E. Matsha, Jose G. Mill, Peter H. Whincup, Lucia Pacifico, Abel López-Bermejo, Carmelo Antonio Caserta, Carla Campos Muniz Medeiros, Anastasios Kollias, Mostafa Qorbani, Fariborz Sharifian Jazi, Gerda-Maria Haas, Rafael de Oliveira Alvim…
    Citation: BMC Medicine 2023 21:442
  18. Large-scale prevention of respiratory syncytial virus (RSV) infection may have ecological consequences for co-circulating pathogens, including influenza. We assessed if and for how long RSV infection alters th...

    Authors: Naomi R. Waterlow, Jackie Kleynhans, Nicole Wolter, Stefano Tempia, Rosalind M. Eggo, Orienka Hellferscee, Limakatso Lebina, Neil Martinson, Ryan G. Wagner, Jocelyn Moyes, Anne von Gottberg, Cheryl Cohen and Stefan Flasche
    Citation: BMC Medicine 2023 21:441

    The Correction to this article has been published in BMC Medicine 2024 22:128

  19. Creatine is an organic compound that facilitates the recycling of energy-providing adenosine triphosphate (ATP) in muscle and brain tissue. It is a safe, well-studied supplement for strength training. Previous...

    Authors: Julia Fabienne Sandkühler, Xenia Kersting, Annika Faust, Eva Kathrin Königs, George Altman, Ulrich Ettinger, Silke Lux, Alexandra Philipsen, Helge Müller and Jan Brauner
    Citation: BMC Medicine 2023 21:440
  20. Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhum...

    Authors: George Y. Qian, W. John Edmunds, Daniel G. Bausch and Thibaut Jombart
    Citation: BMC Medicine 2023 21:439
  21. Breast cancer is the most commonly diagnosed cancer in women worldwide, and underlying mechanistic pathways associated with breast cancer-specific and non-breast cancer-related deaths are of importance. Emergi...

    Authors: Nina Sophia Decker, Theron Johnson, Johannes A. Vey, Charlotte Le Cornet, Sabine Behrens, Nadia Obi, Rudolf Kaaks, Jenny Chang-Claude and Renée Turzanski Fortner
    Citation: BMC Medicine 2023 21:438
  22. People with hypertension have a higher risk of developing Parkinson’s disease (PD), epidemiological evidence suggests that multiple antihypertensives may affect the occurrence and development of PD with incons...

    Authors: Zeying Feng, Qiuping Zhao, Jingjing Wu, Yiping Yang, Xinru Jia, Junlong Ma, Haibo Tang, Hong Yuan, Guoping Yang and Yao Lu
    Citation: BMC Medicine 2023 21:437
  23. Metabolically healthy obesity is hypothesized to be a benign condition but whether this is the case for dementia remains debated. We examined the role of age at assessment of metabolic-obesity phenotypes in as...

    Authors: Marcos D. Machado-Fragua, Séverine Sabia, Aurore Fayosse, Céline Ben Hassen, Frank van der Heide, Mika Kivimaki and Archana Singh-Manoux
    Citation: BMC Medicine 2023 21:436
  24. Infants born very and extremely premature (V/EPT) are at a significantly elevated risk for neurodevelopmental disorders and delays even in the absence of structural brain injuries. These risks may be due to ea...

    Authors: Kevin M. Cook, Josepheen De Asis-Cruz, Jung-Hoon Kim, Sudeepta K. Basu, Nickie Andescavage, Jonathan Murnick, Emma Spoehr, Melissa Liggett, Adré J. du Plessis and Catherine Limperopoulos
    Citation: BMC Medicine 2023 21:435
  25. The widening of group-level socioeconomic differences in body mass index (BMI) has received considerable research attention. However, the predictive power of socioeconomic position (SEP) indicators at the indi...

    Authors: Liam Wright, Charis Bridger Staatz, Richard J. Silverwood and David Bann
    Citation: BMC Medicine 2023 21:434
  26. Genetics play an important role in risk for cardiometabolic diseases—including type 2 diabetes, cardiovascular disease and obesity. Existing research has explored the clinical utility of genetic risk tools suc...

    Authors: Jing Hui Law, Najia Sultan, Sarah Finer and Nina Fudge
    Citation: BMC Medicine 2023 21:432
  27. Elevated standardised mortality ratio of cardiovascular diseases (CVD) in patients with brain tumours may result from differences in the CVD incidences and cardiovascular risk factors. We compared the risk of ...

    Authors: Michael T. C. Poon, Paul M. Brennan, Kai Jin, Cathie L. M. Sudlow and Jonine D. Figueroa
    Citation: BMC Medicine 2023 21:431
  28. Recent studies have highlighted the role of low-grade systemic inflammation in linking periodontitis to cardiovascular disease (CVD) outcomes, but many aspects remain unclear. This study examines the independe...

    Authors: Christiane Pink, Birte Holtfreter, Henry Völzke, Matthias Nauck, Marcus Dörr and Thomas Kocher
    Citation: BMC Medicine 2023 21:430
  29. Vaccination has played a pivotal role in reducing the burden of COVID-19. Despite numerous studies highlighting its benefits in reducing the risk of severe disease and death, we still lack a quantitative under...

    Authors: Mahan Ghafari, Sepanta Hosseinpour, Mohammad Saeid Rezaee-Zavareh, Stefan Dascalu, Somayeh Rostamian, Kiarash Aramesh, Kaveh Madani and Shahram Kordasti
    Citation: BMC Medicine 2023 21:429
  30. Components of social connection are associated with mortality, but research examining their independent and combined effects in the same dataset is lacking. This study aimed to examine the independent and comb...

    Authors: Hamish M. E. Foster, Jason M. R. Gill, Frances S. Mair, Carlos A. Celis-Morales, Bhautesh D. Jani, Barbara I. Nicholl, Duncan Lee and Catherine A. O’Donnell
    Citation: BMC Medicine 2023 21:384
  31. Research on the association between telomere length (TL) and incident non-alcoholic fatty liver disease (NAFLD) is limited. This study examined this association and further assessed how TL contributes to the a...

    Authors: Linxi Tang, Dankang Li, Yudiyang Ma, Feipeng Cui, Jianing Wang and Yaohua Tian
    Citation: BMC Medicine 2023 21:427
  32. Given the widespread implementation of COVID-19 vaccination to mitigate the pandemic from the end of 2020, it is important to retrospectively evaluate its impact, in particular by quantifying the number of sev...

    Authors: Laetitia Tan-Lhernould, Cynthia Tamandjou, Guilhem Deschamps, Johnny Platon, Cécile Sommen, Fanny Chereau, Isabelle Parent du Châtelet, Simon Cauchemez, Sophie Vaux and Juliette Paireau
    Citation: BMC Medicine 2023 21:426
  33. People need high-quality information to make decisions about research participation. Providing information in written format alone is conventional but may not be the most effective and acceptable approach. We ...

    Authors: Vichithranie W. Madurasinghe, Peter Knapp, Sandra Eldridge, David Collier, Shaun Treweek, Jo Rick, Jonathan Graffy, Adwoa Parker, Chris Salisbury, David Torgerson, Kate Jolly, Manbinder S. Sidhu, Christopher Fife-Schaw, Mark A. Hull, Kirsty Sprange, Elizabeth Brettell…
    Citation: BMC Medicine 2023 21:425
  34. Antidepressants are licensed for use in depressive disorders, but non-response and poor adherence to treatment affect a considerable number of patients. Pre-clinical and clinical evidence suggest that statins ...

    Authors: Riccardo De Giorgi, Franco De Crescenzo, Philip J. Cowen, Catherine J. Harmer and Andrea Cipriani
    Citation: BMC Medicine 2023 21:424
  35. Treatment options beyond the first-line setting for recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) are limited. The role of the multitarget tyrosine kinase inhibitor anlotinib in RM-NPC is unclear.

    Authors: Yu Fang, Ning Su, Qihua Zou, Yi Cao, Yi Xia, Linquan Tang, Xiaopeng Tian, Panpan Liu and Qingqing Cai
    Citation: BMC Medicine 2023 21:423
  36. Maternal pre-gestational diabetes (PGDM), gestational diabetes mellitus (GDM), and overweight/obesity have been associated with increased risks of offspring neurodevelopmental conditions (NDCs) including autis...

    Authors: Shuyun Chen, Xi Wang, Brian K. Lee and Renee M. Gardner
    Citation: BMC Medicine 2023 21:422
  37. Reactive astrogliosis has been demonstrated to have a role in Parkinson’s disease (PD); however, astrocyte-specific plasma glial fibrillary acidic protein (GFAP)’s correlation with PD progression remains unkno...

    Authors: Junyu Lin, Ruwei Ou, Chunyu Li, Yanbing Hou, Lingyu Zhang, Qianqian Wei, Dejiang Pang, Kuncheng Liu, Qirui Jiang, Tianmi Yang, Yi Xiao, Bi Zhao, Xueping Chen, Wei Song, Jing Yang, Ying Wu…
    Citation: BMC Medicine 2023 21:420
  38. Accumulating evidence has suggested an oncogenic effect of diurnal disruption on cancer progression. To test whether targeting circadian rhythm by dietary strategy suppressed lung cancer progression, we adopte...

    Authors: Dan Shi, Gaofeng Fang, Qianyao Chen, Jianling Li, Xiongzhong Ruan and Xuemei Lian
    Citation: BMC Medicine 2023 21:417
  39. Progressive reduction of sodium intake is an attractive approach for addressing excessive salt intake, but evidence for this strategy in real practice is limited. We aimed to determine the feasibility, effecti...

    Authors: Yifang Yuan, Aoming Jin, Peifen Duan, La’e Cao, Hongxia Wang, Senke Hu, Jiayu Li, Xiangxian Feng, Qianku Qiao, Hui Zhang, Ruijuan Zhang, Huijuan Li, Pei Gao, Gaoqiang Xie, Jianhui Yuan, Lili Cheng…
    Citation: BMC Medicine 2023 21:416
  40. Sepsis is characterized by a dysregulated immune response and metabolic alterations, including decreased high-density lipoprotein cholesterol (HDL-C) levels. HDL exhibits beneficial properties, such as lipopol...

    Authors: Alessandra Stasi, Marco Fiorentino, Rossana Franzin, Francesco Staffieri, Sabrina Carparelli, Rosa Losapio, Alberto Crovace, Luca Lacitignola, Maria Teresa Cimmarusti, Francesco Murgolo, Monica Stufano, Cesira Cafiero, Giuseppe Castellano, Fabio Sallustio, Chiara Ferrari, Mario Ribezzi…
    Citation: BMC Medicine 2023 21:392
  41. The early life stage is critical for the gut microbiota establishment and development. We aimed to investigate the lifelong impact of famine exposure during early life on the adult gut microbial ecosystem and ...

    Authors: Wanglong Gou, Huijun Wang, Xin-yi Tang, Yan He, Chang Su, Jiguo Zhang, Ting-yu Sun, Zengliang Jiang, Zelei Miao, Yuanqing Fu, Hui Zhao, Yu-ming Chen, Bing Zhang, Hongwei Zhou and Ju-Sheng Zheng
    Citation: BMC Medicine 2023 21:414
  42. Cardiac fibrosis is one of the top killers among fibrotic diseases and continues to be a global unaddressed health problem. The lack of effective treatment combined with the considerable socioeconomic burden h...

    Authors: Milena Paw, Agnieszka A. Kusiak, Kinga Nit, Jacek J. Litewka, Marcin Piejko, Dawid Wnuk, Michał Sarna, Kinga Fic, Kinga B. Stopa, Ruba Hammad, Olga Barczyk-Woznicka, Toni Cathomen, Ewa Zuba-Surma, Zbigniew Madeja, Paweł E. Ferdek and Sylwia Bobis-Wozowicz
    Citation: BMC Medicine 2023 21:412
  43. With increasing hypercholesterolemia prevalence in East Asian adolescents, pharmacologic interventions (e.g., HMGCR inhibitors (statins) and PCSK9 inhibitors) may have to be considered although their longer-te...

    Authors: Shan Luo, Hugh Simon Lam, Yap Hang Chan, Clara Sze Man Tang, Baoting He, Man Ki Kwok, Gabriel M. Leung, C Mary Schooling and Shiu Lun Au Yeung
    Citation: BMC Medicine 2023 21:410
  44. The gut mycobiome of patients with lung adenocarcinoma (LUAD) remains unexplored. This study aimed to characterize the gut mycobiome in patients with LUAD and evaluate the potential of gut fungi as non-invasiv...

    Authors: Qingyan Liu, Weidong Zhang, Yanbin Pei, Haitao Tao, Junxun Ma, Rong Li, Fan Zhang, Lijie Wang, Leilei Shen, Yang Liu, Xiaodong Jia and Yi Hu
    Citation: BMC Medicine 2023 21:409
  45. Black Americans suffer disparities in risk for cardiometabolic and other chronic diseases. Findings from the Adventist Health Study-2 (AHS-2) cohort have shown associations of plant-based dietary patterns and ...

    Authors: Fayth M. Butler, Jason Utt, Roy O. Mathew, Carlos A. Casiano, Suzanne Montgomery, Seth A. Wiafe, Johanna W. Lampe and Gary E. Fraser
    Citation: BMC Medicine 2023 21:408
  46. Unprofessional behaviour (UB) between staff encompasses various behaviours, including incivility, microaggressions, harassment, and bullying. UB is pervasive in acute healthcare settings and disproportionately...

    Authors: Jill Maben, Justin Avery Aunger, Ruth Abrams, Judy M. Wright, Mark Pearson, Johanna I. Westbrook, Aled Jones and Russell Mannion
    Citation: BMC Medicine 2023 21:403