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Table 6 Unadjusted* RRs for immune-mediated diseases following admission for rickets, osteomalacia or vitamin D deficiency, combined

From: Hospital admissions for vitamin D related conditions and subsequent immune-mediated disease: record-linkage studies

Autoimmune condition

O

E

RR (95% CI)

P-value

Ankylosing spondylitis

16

9.3

1.73 (0.99 to 2.81)

0.04

Asthma (aged 5 to 54)

150

393

0.38 (0.32 to 0.45)

<0.001

Celiac disease

78

15.8

4.96 (3.91 to 6.19)

<0.001

Crohn’s disease

47

23.2

2.03 (1.49 to 2.7)

<0.001

Diabetes mellitus (aged 0 to 29)

20

6.3

3.2 (1.96 to 4.95)

<0.001

Multiple sclerosis

15

16.4

0.92 (0.51 to 1.51)

0.826

Rheumatoid arthritis

158

147.2

1.07 (0.91 to 1.25)

0.397

Ulcerative colitis

32

28.9

1.11 (0.76 to 1.56)

0.626

  1. O Observed number of cases, E Expected number, RR Rate ratio, 95% CI 95% confidence interval.
  2. * See Methods section and legend for Table 2.
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BMC Medicine

ISSN: 1741-7015

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